Liver function tests: TBL - Week 6 Flashcards
What is the best clinical sign of jaundice?
Yellow sclera
Give some features of liver failure.
Abnormalities of Bilirubin & prothrombin time, presence of ascites and encephalopathy
Liver function tests include…
Bilirubin, Albumin, Prothrombin time
Liver damage tests include…
ALT & Gamma GGT
Give examples of Cholestatic LFTs.
Alkaline phosphatase, Gamma GGT
Raised Cholestatic LFTs suggest…
Tumour or gallstones (biliary pathology)
Which test is performed for Hepatitic/Hepatocellular LFTs?
ALT
What test results would be obtained for a patient with hepatitis?
Raised ALT/AST
Normal alk phos/gGGT
What test results would be obtained for a patient with biliary pathology?
Normal ALT/AST
Raised Alkaline phosphatase, Gamma GGT
Liver screening would involve…
Full blood count U&Es Clotting LFTs Liver immunology HBV & HCV Alpha-1-antitrpsin, caeruloplasmin
A patient with recent Flucloxacillin use has raised ALT/AST but normal alk phos/gGGT. What is the likely diagnosis?
Drug-induced hepatitis
What is meant by MRCP?
Magnetic resonance cholangiopancreatography or MRCP uses a powerful magnetic field, radio waves and a computer to evaluate the liver, gallbladder, bile ducts, pancreas and pancreatic duct for disease.
What is meant by ERCP?
Endoscopic Retrograde Cholangio-Pancreatography - insert tube into stomach & first part of duodenum then up into bile ducts
What do the following results suggest?
Raised ALT/AST
Normal alk phos/gGGT
Hepatitis/hepatocellular injury
What do the following results suggest?
Normal ALT/AST
Raised Alkaline phosphatase, Gamma GGT
Biliary pathology - tumour or gallstones
