*Lung Cancer Flashcards Preview

Study notes - Respiratory > *Lung Cancer > Flashcards

Flashcards in *Lung Cancer Deck (23):
1

How can tissue biopsies be taken to diagnose lung cancer? (4)

Bronchoscopy
CT guided biopsy
Lymph node biopsy
Aspiration of pleural fluid

2

What is used to assess a patients fitness for chemotherapy?

ECOG score

3

How can a tissue sample be taken during bronchoscopy?

Biopsy
Brush cytology

4

What is endobronchial ultrasound used to visualise?

Hilar and mediastinal structures

5

What are the 5 main types of lung cancer?

Small cell
Non--small cell:
Squamous cell
Adenocarcinoma
Large cell
Bronchoalveolar cell

6

What ectopic hormone can small cell lung cancer secrete?

ACTH

7

What is the most common type of lung cancer?

Adenocarcinoma (followed by scam cell, then small cell, then large cell, then bronchoalveolar cell)

8

What is the most common type of lung cancer in non-smokers?

Adenocarcinoma

9

What type of cancer hardly ever occurs in non-smokers?

Small cell

10

Treatment of small cell lung cancer?

Chemosensitive (usually becomes rapidly resistant) backed up with radiation
Usually disseminated on diagnosis therefore no surgery

11

What lung cancer has the worst survival stats?

Small cell lung cancer

12

Is small cell normally central or peripheral?

Central

13

How are non-small cell lung cancers normally treated?

Surgery (can be backed up with radiotherapy) is normally the curative treatment of choice
If it is more than stage T1 however surgery is not usually performed - there are chemo/radiotherapy regimens been developed but not very sucessful

14

What type of lung cancer can histologically look like lymphocytes and therefore mimic lymphoma?

Small cell

15

Is squamous cell normally central or peripheral?

Central

16

What type of ectopic hormone does squamous cell carcinoma secrete?

PTH (if high levels, can cause Ca to leave bone for blood)

17

What can express p63 and high molecular weight cytokeratins?

Squamous cell

18

What type of lung cancer has the highest survival rates?

Adenocarcinoma

19

Are adenocarcinoma tumours normally central or peripheral?

Periperhal

20

What type of cancer normally has mutations in EFGR?

Adenocarcinoma (respond to tyrosine kinase inhibitors e.g. erlotinib)

21

What type of tumour can express TTF1?

Adenocarcinoma

22

What is mucin producing tumour?

Adenocarcinoma

23

What are the types endobronchial therapy?

Stent for stridor
Photo-dynamic therapy
Other laser therapy
Radio-active pellets