Flashcards in *Lung Cancer Deck (23)
How can tissue biopsies be taken to diagnose lung cancer? (4)
CT guided biopsy
Lymph node biopsy
Aspiration of pleural fluid
What is used to assess a patients fitness for chemotherapy?
How can a tissue sample be taken during bronchoscopy?
What is endobronchial ultrasound used to visualise?
Hilar and mediastinal structures
What are the 5 main types of lung cancer?
What ectopic hormone can small cell lung cancer secrete?
What is the most common type of lung cancer?
Adenocarcinoma (followed by scam cell, then small cell, then large cell, then bronchoalveolar cell)
What is the most common type of lung cancer in non-smokers?
What type of cancer hardly ever occurs in non-smokers?
Treatment of small cell lung cancer?
Chemosensitive (usually becomes rapidly resistant) backed up with radiation
Usually disseminated on diagnosis therefore no surgery
What lung cancer has the worst survival stats?
Small cell lung cancer
Is small cell normally central or peripheral?
How are non-small cell lung cancers normally treated?
Surgery (can be backed up with radiotherapy) is normally the curative treatment of choice
If it is more than stage T1 however surgery is not usually performed - there are chemo/radiotherapy regimens been developed but not very sucessful
What type of lung cancer can histologically look like lymphocytes and therefore mimic lymphoma?
Is squamous cell normally central or peripheral?
What type of ectopic hormone does squamous cell carcinoma secrete?
PTH (if high levels, can cause Ca to leave bone for blood)
What can express p63 and high molecular weight cytokeratins?
What type of lung cancer has the highest survival rates?
Are adenocarcinoma tumours normally central or peripheral?
What type of cancer normally has mutations in EFGR?
Adenocarcinoma (respond to tyrosine kinase inhibitors e.g. erlotinib)
What type of tumour can express TTF1?
What is mucin producing tumour?