*Pleural disease 2 (pulmonary vascular and pleural pathology) Flashcards Preview

Study notes - Respiratory > *Pleural disease 2 (pulmonary vascular and pleural pathology) > Flashcards

Flashcards in *Pleural disease 2 (pulmonary vascular and pleural pathology) Deck (11):
1

Is the pulmonary circulation a low or high pressure system?

Low pressure system (therefore thin walled vessels and a low incidence of atherosclerosis at normal pressures)

2

What is pulmonary oedema?
what type of pattern of lung disease does this cause?

Accumulation of fluid in the lung interstitium and alveolar spaces
Restrictive pattern

3

Causes of pulmonary oedema?

Haemodynamic (increased hydrostatic pressure)
Cellular injury (alveolar lining cells, alveolar endothelium) e.g. pneumonia, Adult respiratory distress syndrome

4

What are 2 other names for adult respiratory distress syndrome?

Diffuse alveolar damage syndrome
Shock lung

5

What are causes of ARDS?

Sepsis
Diffuse infection (virus, mycoplasma)
Severe trauma
Oxygen

6

Pathogenesis of ARDS?

Injury e.g. bacterial endotoxin causing:
Infiltration of inflammatory cells
Cytokines
Oxygen free radicals
Injury to cell membranes

7

Pathology of ARDS?

Fibrinous exudate lining alveolar walls
Cellular regeneration
Inflammation

8

Outcome of ARDS?

Death
Resolution
Fibrosis (chronic restrictive lung disease)

9

What type of babies get neonatal RDS?
Why?
What causes the physical damage to cells?

Premature infants
Deficient in surfactant
Increased effort in expanding the lungs = physical damage to cells

10

What type of emboli are 95%?

Thromboemoli - can however be gas, fat, foreign bodies and tumour clumps

11

What can recurrent small pulmonary emboli lead to?

Pulmonary hypertension