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Study notes - Respiratory > *Biochemistry > Flashcards

Flashcards in *Biochemistry Deck (21):
1

What is accuracy?

How close the result is to the true value

2

What is precision?

How predictable your results are

3

What is a false positive?

A healthy person who's result is in the disease territory and which therefore acts as a false alarm

4

What is a false negative?

A diseases whose result sin the healthy territory and which is therefore falsely reassuring

5

What is sensitivity?

The percentage of those of who have the disease who are correctly identified by a positive test result

6

What is specificity?

The proportion of those who do not have the disease who are correctly identified by a negative test result

7

What is the positive predictive value?

The proportion of those who test positive who actually have the disease

8

What is the negative predictive value?

The proportion of those who test negative who do not have the disease

9

What happens to PPV and NPV as the prevalence of a disease falls?

They both fall

10

When is there not much value in carrying out an investigation in terms of prevalence? Why?

When the prevalence is very low or very high - the PPV isn't very different from the probability - most useful when the prevalence is approximately 50%

11

What is the most sensitive biochemistry marker for an MI?

Creatinine kinase

12

What causes the release of enzymes into the blood during pancreatitis?

Acute and chronic pancreatitis causes the release of some of the pancreases digestive enzymes into the pancreas itself, where they digest pancreatic tissue, releasing amylase and lipase into the blood

13

What is a dynamic function test?

Where a particular endocrine "axis" is tested dynamically, either by suppressing it or stimulating it in some way

14

Is normal urine acidic or alkaline?

Acidic

15

How is carbonic acid removed?

As CO2

16

What neutralises H+?

H2CO3

17

What is formed when H+ and bicarbonate combine?

Carbonic acid (removed as CO2)

18

What is acidaemia?

Increased [H+]

19

What is alkalaemia?

Decreased [H+]

20

What is acidosis?

Process tending to cause increased [H+]

21

What is alkalosis?

Process tending to cause decreased [H+]