Flashcards in lung cancer Deck (10):
what is a marker for lung adenocarcinoma?
mutation in k-ras oncogene can lead to what type of lung cancer
where is adenocarcenoma of lung found?
periphery of lung
where is large cell carcenoma of the lung found
what features define large cell carcinoma
anaplastic undifferentiated cells with giant cells of variouos pleomorphisms
does large cell carcinoma of lung respond to chemo?
no - very poor prognosis
what type of lung cancer presents in the center of lung as a hilar mass or cavitated lesion on x-ray or chest CT that also shows keratin pearls on histology?
squamous cell lung carcinoma
which type of lung cancer is likely to secrete PTHrP?
squamous cell carcinoma
finding is high calcium with low PTH
what featues differentiatee squamous cell from small cell carcinoma?
both are centrally located
small cell has very small nucleus to cytoplasm ratio
small cell is morelykely to secrete ATCH and ADH
small cell can have cells which produce auto-antibodies against calcium channels (lamert-eaton)