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Flashcards in lung cancer Deck (10):
1

what is a marker for lung adenocarcinoma?

CEA

2

mutation in k-ras oncogene can lead to what type of lung cancer

adenocarcinoma

3

where is adenocarcenoma of lung found?

periphery of lung

4

where is large cell carcenoma of the lung found

periphery

5

what features define large cell carcinoma

anaplastic undifferentiated cells with giant cells of variouos pleomorphisms

6

does large cell carcinoma of lung respond to chemo?

no - very poor prognosis

7

what type of lung cancer presents in the center of lung as a hilar mass or cavitated lesion on x-ray or chest CT that also shows keratin pearls on histology?

squamous cell lung carcinoma

8

which type of lung cancer is likely to secrete PTHrP?

squamous cell carcinoma

finding is high calcium with low PTH

9

what featues differentiatee squamous cell from small cell carcinoma?

both are centrally located

small cell has very small nucleus to cytoplasm ratio

small cell is morelykely to secrete ATCH and ADH

small cell can have cells which produce auto-antibodies against calcium channels (lamert-eaton)

10

what is a potential complication of bronchogenic carcinoma?

superior vena cava syndrome - obstruction of superior venacava by pancoast tumor (aka superior sulcus tumour; aka when a tumor from a primary bonchogenic carcinoma arises in the lung apex and invades the surrounding soft tissues.)

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