Lung Microanatomy/Lung Histology Flashcards Preview

CVPR: Pulmonary > Lung Microanatomy/Lung Histology > Flashcards

Flashcards in Lung Microanatomy/Lung Histology Deck (11)
1

Main conducting airways and lung lobes

  • larynx ==> trachea ==> L and R primary bronchi ==> secondary/lobar bronchi ==> lobes of lung ==> bronchioles ==> terminal bronchioles ==> respiratory bronchioles
  • R lobes: upper right, middle right, and lower right
  • L lobes: upper left, lower left

2

Containment structure surrounding lungs

  • pleural layers ==> pleural cavity that holds lungs
  • lung covered by visceral pleura (mesothelium + etc.)
  • parietal pleura lies against connective tissue of ribs

3

Histologic composition of trachea

  • "c-shaped" cartilagenous rings
  • rings connected posteriorly by trachealis muscle
  • inner pseudostratified epithelia layer

  • submucosa of connective tissue
     

  • lamina propria = mucosa
  • epithelium = ciliated epithelial, goblet cells, basal cells, neuroendocrine cells

4

Histologic composition of large bronchi


  • "c-shaped" cartilagenous rings

    r extending around entire diameter 





  • inner pseudostratified epithelia layer 
  • muscularis smooth muscle between epithelial layer and submucosa






  • submucosa of connective tissue 

  • lamina propria = mucosa
  • epithelium = ciliated epithelial, goblet cells, basal cells, neuroendocrine cells

 

 

5

Fxn of various epethial/submucosa cells

  • cila ==> helps push out pollutants
  • goblet cells ==> secret mucins and other proteins
  • submucosa glands ==> mucus + secretions to mucosal surface

6

Histology of bronchioles

  • smaller airways
  • no cartilage
  • smooth muscle 
  • epithelium w/cilia and goblet cells
  • ==> terminal bronchioles = increasing numbers of Clara cells ==> secret surface-active substances

7

Begining of gaseos exchange system composition

  •  terminal bronchioles ==> respiratory bronchioles ==> alveoli
  • respiratory bronchioles = epithelium w/Clara cells + smooth muscle layer
  • alveolar ducts ~ alveolar-bound channels
  • gas exchange @ alveolar saccules

8

Alveoli structure

  • chambers separated by interalveolar septa
  • Type I & Type II pneymocytes = cells on alveolar septa facing air supplu
    • Type I = thin, flat cover most of surface facing air supply
    • Type II = rounded, progenitors of type I cells, ganules w/surfactant ==> lowers surface tension in alveoli and prevents lung collapse and excessive drying

9

Air-blood barrier = 

  • the surfactant layer==>
  • the plasma membranes and cytoplasm of  thin type I cell ==>
  • common basal lamina between the type I cell and the capillary epithelium ==>
  • plasma membranes and cytoplasm of the endothelial cell

10

Components of alveor defense

  • loose connective tissue @ alveolar septa contains monocytes, neutrophils, and fibroblasts
  • monocytes ==> alveolar macrophages ==> can enter alveolar space 

11

Lung vasculature components

  • systemic arteries (bronchial arteries from aorta) ==> supply O2 to conduction system
  • pulmonary arteries from RV ==> alveoli ==> pulmonary veins ==> LA