Lung Neoplasms and Malignancies Flashcards Preview

Pulmonology 2 > Lung Neoplasms and Malignancies > Flashcards

Flashcards in Lung Neoplasms and Malignancies Deck (19):
1

What are the risk factors for lung cancer?

Cigarettes
Occupational
Ionizing Radiation
Env Tobacco Smoke
Pum Fibrosis
Radon
Chronic Bonchitis
P450 Polymorphisms
Chromosome Fragility

2

What are the most common Signs and Symptoms of Lung Cancer?

Cough
Weight loss
Dyspnia
Chest Pain

3

What is the first step in evaluating a CXR abnormality?

LOOK AT AN OLD CXR TO COMPARE!
After that CT for size/location/charicteristics

4

How can you tell the difference between cancerous and benign Solitary pulmonary nodules?

.

5

What are the most common cancers that metastasize to the lung?

Breast
Colorectal
Prostate
Cervical
Endometrial

6

What are the types of lung malignancy?

Small cell lung cancer

Non-Small Cell Lung Cancer
-Squamous Cell CA
-AdenoCA
Large Cell CA

Meothelioma

7

What is charicteristic of Small cell lung cancer?

.

8

What is charicteristic of AdenoCA of the lung?

#1 cancer in non-smokers
Cancer of young women
Bronchoalveolar, no invasion, grows along alveoli- solitary mass, fluffy infiltrates, ground glass

9

What is charicteristic of Large Cell CA?

Lower incidence
Peripherally located
Large cells with poor differentiation
Sheets of cells with necrosis
Cavitiating mas
late distant metastasis

10

What are the Lung cancer associated Complications?

Horner Syndrome
-Miosis, anhydrosis, ptosis
-invasion of cervical ganglion
-apical tumors
Pancoast's Syndrome
-Horner's + Brachial Plexus
Superior VC Syndrome

11

What are Paraneoplastic Syndromes associated with Lung cancer?

Squ Cell CA
-hyperCalcemia
Small Cell
-Cushing's
-SIADH
-Eaton Lambert Synd (gets stonger with repeated motion)
AdenoCA
-DIC, Thrombophlebitis, Microangiopathic hemolytic anemia
Large Cell CA
-Gynecomastia

12

Waht are the most likely metasastic sites of cancer?

Liver
Brain
Bone
Adrenal

13

How is Cancer diagnosed?

EBUS(Endobronchial ultrasound guided biopsy)
Biopsy a palpable LN
Biopsy of metastatic lesion or
Eval of pleural effusion

14

What are the indications of Low dose CT scan?

Age 55-74
>30 pack year smoking history
Current smoker or have quit within the last 15 years
In relatively good health

15

What is the staging system of Lung cancer?

TNM = Tumor, node, Metastasis

16

What charicteristics make a Tumor Stage 4? other?

ANY METASTATIC LESION = STAGE4
The bigger the tumor, the higher the stage
If it invades other mediastinal structures, it will be T4

17

What are the different Treatments for Lung cancer?

Palliative to improve QOL
Non Small Cell
Small Cell

18

What are the Biologic Treatments for Lung cancer?

Nivolumab
Pembrolizumab
Both Monoclonal IgG4 Ab

19

What are the most common causes of Benign Pulmonary Neoplasms?

Hamartomas
-peripheral
-normal tissue

Bronchial Adenoma
-central, slow growing, endobronchial
Chronic cough, hemoptysis