Flashcards in Lung Neoplasms and Malignancies Deck (19):
What are the risk factors for lung cancer?
Env Tobacco Smoke
What are the most common Signs and Symptoms of Lung Cancer?
What is the first step in evaluating a CXR abnormality?
LOOK AT AN OLD CXR TO COMPARE!
After that CT for size/location/charicteristics
How can you tell the difference between cancerous and benign Solitary pulmonary nodules?
What are the most common cancers that metastasize to the lung?
What are the types of lung malignancy?
Small cell lung cancer
Non-Small Cell Lung Cancer
-Squamous Cell CA
Large Cell CA
What is charicteristic of Small cell lung cancer?
What is charicteristic of AdenoCA of the lung?
#1 cancer in non-smokers
Cancer of young women
Bronchoalveolar, no invasion, grows along alveoli- solitary mass, fluffy infiltrates, ground glass
What is charicteristic of Large Cell CA?
Large cells with poor differentiation
Sheets of cells with necrosis
late distant metastasis
What are the Lung cancer associated Complications?
-Miosis, anhydrosis, ptosis
-invasion of cervical ganglion
-Horner's + Brachial Plexus
Superior VC Syndrome
What are Paraneoplastic Syndromes associated with Lung cancer?
Squ Cell CA
-Eaton Lambert Synd (gets stonger with repeated motion)
-DIC, Thrombophlebitis, Microangiopathic hemolytic anemia
Large Cell CA
Waht are the most likely metasastic sites of cancer?
How is Cancer diagnosed?
EBUS(Endobronchial ultrasound guided biopsy)
Biopsy a palpable LN
Biopsy of metastatic lesion or
Eval of pleural effusion
What are the indications of Low dose CT scan?
>30 pack year smoking history
Current smoker or have quit within the last 15 years
In relatively good health
What is the staging system of Lung cancer?
TNM = Tumor, node, Metastasis
What charicteristics make a Tumor Stage 4? other?
ANY METASTATIC LESION = STAGE4
The bigger the tumor, the higher the stage
If it invades other mediastinal structures, it will be T4
What are the different Treatments for Lung cancer?
Palliative to improve QOL
Non Small Cell
What are the Biologic Treatments for Lung cancer?
Both Monoclonal IgG4 Ab