Flashcards in Non-Infectious Inflammatory Diseases Deck (23):
What is Sarcoidosis?
A multisystem granulomatous disease of unknown etiology
Who does sarcoidosis affect?
(young and middle aged adults)
No gender difference
African american and caucasians
Have had past exposure to insectisides, agric. employment, and microbial bioaerosols
What is the clinical presentation of sarcoidosis?
Most commonly: Lung involvement
Uveo-parotid fever = Heerford's syndrome
Bilateral Hilar lymphadenopathy
How can diseases similar to Sarcoidosis be ruled out? Tests?
PE: adenopathy, skin lesions,
Labs: Ca level, liver Ez, creatinine
TB skin test
WHat is seen on the Pulmonary Function test in Sarcoidosis?
Restrictive: Normal shape with smaller volumes
Dec Total Lung Capacity
Dec Vital Capacity
Dec Rreserve Volume
Dec Diffusion Capacity (CO)
What is the appearance of the stages of development of Sarcoidosis on CXR?
Stage 1: Hilum
St 2: consolidation(haziness)
St 3: no lymphadenopathy only infiltrates
St 4: Extensive fibrotic Change in lung
What is the appearance of Sarcoidosis on Chest CT?
What are the diagnositic procedures used for Sarcoidosis?
What is the treatment of Sarcoidosis?
Systemic Corticosteroids in systemic involvement
What are the connective tissue diseases that can effect the lungs?
Dermatomyositis and polymyositis
What is the presentation of Rheumatoid lung diasease?
Dyspnea on exertion
May precede joint disease by years
What medications are used for Rheumatoid lung diasease?
What is the most common cause of death in Scleroderma?
What are the different presentations of scleroderma?
Interstitial Lung disease
Limited form(CREST Syndrome)
What is included in CREST syndrome?
What is seen in Pulmonary involvement of SLE?
Acute and Chronic Lupus Pneumonitis
Increased risk for DVT/PE
What is the Presentaion of Sjogren's syndrome in the lung?
Bronchiectasis and bronchiolitis
How can you tell if an airway is dilated on CT?
The airway is wider than the BV that runs with it.
What is the presentation of Pulmonary Vasculitis?
Churg Strauss synd
Diffuse Alveolar hemmorhage
How is wegener's granulomatosis differentiated from TB?
What is seen in CXR of Goodpasture's syndrome?
Bleeding from Alveoli
Need to do bronchoscopy
What is the Triad seen in Churg Strause Syndrome?
Asthma, hypereosinophelia, necrotizing vasculitis