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Flashcards in Viral resp infections Deck (19):
1

What are the symptoms of the common cold?

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2

How are common cold symptoms different than LRT infection?

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3

What viruses cause the common cold?

Rhinovirus
Coronavirus

4

What viruses cause more serious resp tract infections

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5

What are the Epidemiology any symptoms of SARS and MERS?

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6

What are the typical symptooms of Influenza?

fever, myalgia, headache, shaking, chills and cough peaking between 3-5 days
cough, fatigue and weakness may last 2-6 wks

7

What 4 patient groups are associated with increased risk for influenza complications?

Diabetics
Children

8

What differentiates the 4 different influenza antiviral agents?

Zanamivir and Oseltamivir for Type A and B
Zan = Inhalation
Osel = Oral

9

What is the difference between bacterial pneumonia following influenza and and 1^ influenza pneumonia?

Bact after viral:
Biphasic, 7 day onset
Bacterial Cells on gram stain

1^ inf pnu
Progressive worsening
1-4 day onset
no sputum gram stain

10

What are the 3 categories of influenza vaccines and what are their eligibiltiy reqirements ?

Live attenuated- healthy non-pregnant 2-49yo
Inactivated (chronic med cond)
-IM->6mon
-ID-18-64yo
Recombinant (18-49)

11

What are the Clinical presentation and symptoms of CMV pneumonitis?

Owl's Eye inclusions charicteristic of CMV on smear
Malaise, fatigue, spiking fever, mild dyspnea,
Pneumonitis: Interstitial infiltrates, and Hypoxia

12

What is the incidence and transmission of CMV?

Immuno compromized individuals
-Transplant Recipients
-Adv HIV infections
Asymptomatic in Imm-competent

Can be transmitted intrauterine, through breast milk, sexual transmission, saliva and genital secretions, blood, via transplanted organs

13

What is the use of ^Gancyclovir, ^valacyclovir, foscarnet, Cidofovir in treatment and prevention of CMV?

Gan: DNA Polymerase is the target
Viral Thymidine Kinase targets the drug

14

What is the Respiratory disease associated with HSV?

Pneumonitis

15

What is the Respiratory disease associated with VZV?

Secondary Bacterial Infections

16

What is the Respiratory disease associated with EBV?

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17

What is the High dose Inactivated Inf virus?

Sanofi Pasteur

18

What is the standard dose Inactivated Inf virus?

Novartis

19

What is the Prophylaxis and preemptive therapy for CMV?

Antivirals given to transplant Pts