Lymphatics Flashcards

(71 cards)

1
Q

the specialized lymphatic capillaries located in the lining of the small intestine are called?

A

lacteals

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2
Q

organs of the lymphatic?

A

spleen, thymus, and tonsils

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3
Q

from lymphatic capillaries, where does lymph flow directly to?

A

lymphatic vessels; then L or R subclavian vein

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4
Q

Which feature of the lymphatic capillaries allows fluid to enter from the interstitial space but prevents the lymph from returning to the interstitial space.

valve-like reason

A

overlapping squamous cells of vessel walls

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5
Q

structure of fluid flow in order

blood travels to and from to become lymph

A
  1. blood capillaries (blood)
  2. interstitial spaces (interstitial fluid)
  3. lymphatic capillaries (lymph)
  4. lymphatic vessels (lymph)
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6
Q

lymphatic vessels are present in most tissue of the body except?

5 siya, what r those?

A

CNS, Bone Marrow, Cartilage, Epidermis, and Cornea

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7
Q

does lymph have red bloodz in it?

yes or no

A

no. rbcs are too large (same w/ protein)

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8
Q

factors affecting lymph flow

3 siya

A
  1. smooth muscle contractions (of lymph vessels)
  2. skelet muscle contracting around vessels
  3. pressure changes in the thorax during breathing
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9
Q

the main type of fiber comprising lymphatic tissue is?

A

reticular fiber

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10
Q

the majority of lymph is drained where?

right lymph duct or thoracic?

A

thoracic duct

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11
Q

what tonsil is also known as adenoids?

A

pharyngeal tonsils

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12
Q

lymphatic structures found between the oral cavity and the nasal cavity/pharynx?

A

tonsils

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13
Q

most important and most prevalent type of wbc that comprises lymphatic organs?

A

lymphocyte

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14
Q

Lymph nodes are surrounded by a tough connective tissue ___ that extends into the node to form ______, which subdivide the lymph node.

A

capsule; trabeculae

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15
Q

The space between aggregates of lymphatic tissue that contains a network of fibers with attached macrophages

A

lymphatic sinus

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16
Q

Which structure divides lymph nodes into different compartments?

A

Trabeculae

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17
Q

If germinal centers contain lymphocytes, where r the macrophages?

A

lymphatic sinuses

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18
Q

tough connective tissue that surrounds lymph nodes?

A

capsule

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19
Q

these are extensions of the capsules that extends into the node

these subdivide a node in2 areas containing lymphatic tissue & sinuses

A

trabeculae

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20
Q

is the spleen responsible for lymph filtration?

yes or no

A

no, spleen filters blood instead of lymph

may also act as a blood reservoir, and kill old nd dmged rbcs

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20
Q

is the spleen responsible for lymph filtration?

yes or no

A

no, spleen filters blood instead of lymph

may also act as a blood reservoir, and kill old nd dmged rbcs

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21
Q

the lymphatic tissue surrounding the arteries within the spleen

A

white pulp

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22
Q

this pulp is associated with the veins nd consists of a fibrous network, filled with macrophages & rbcs, and enlarged capillaries that connect to the veins

A

red pulp

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23
Q

the ability to resist damage from foreign substances and cancer cells

A

immunity

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24
site of T cell maturation
thymus
25
cells produced in the red bone marrow that may either mature in the marrow or thymus and then **reside in lymphatic tissue**
lymphocytes
26
when response is rapid but fixed, it is known as what type of immunity?
innate immunity | adaptive takes longer kasi nga *nag-aadapt*
27
specificity and memory are characteristics of what type of immunity?
adaptive
28
what happens when an individual does not have a thymus? a. they will not have any immunoprotection b. they will not have mature b-cells in circulation c. they will not be able to produce complement d. they will not have mature t-cells in circulation
D. they will not have mature t-cells in circulation | considering pati na thymus is responsible for t-cell maturation
29
A group of approximately 20 plasma proteins that circulate in the blood, normally in inactive form, is called
complement
30
complement can be activated by combining with? | 2 sila
(1) parts of a bacterial cell & (2) antibodies
31
the effects when commplement is activated
1. promotion of inflammatory response 2. increased phagocytosis 3. lysing of cells
32
white blood cell movement towards damaged tissue in response to chems released by the tissue and other cells
chemotaxis | basta taxi hehe
32
the most important component of the immune system
WBCs
33
accumulation of dead cells, fluids, and tissue debris at the site of infection is called
pus
34
leukocytes in the blood that release histamine and leukotrienes and promote inflammation
basophil
35
cells that are nonmotile and found in connective tissue | (contribute in histamine and leukotriene release)
mast cells
36
the leukocyte that composes 15% of all lymphocyte is?
NK cell (natural killer)
37
Virus and tumors are recognized by what leukocyte in innate immunity?
Natural Killer Cells
38
Immune cell & complement activation can occur as a result of?
Inflammation
39
two types of inflammation
local (specific region) nd systemic (throughout the body)
40
chemicals that **stimulate fever production** to enhance phagocytosis and inhibits replication of some microorgz
pyrogens
41
___ are substances that stimulate adaptive immune responses
Antigens
42
two types of antigens
foreign and self
43
this refers to an overreaction of the immune system to a foreign antigen
allergic reaction
44
When self-antigens stimulate unwanted tissue destruction, ___ disease can be the result.
autoimmune
45
Proteins that bind and respond to specific antigens are called
antibodies | immunoglobulins
45
B cells and antibodies are the primary components of what type of adaptive immunity
antibody-mediated
46
what part of the lymphocytes combine with specific antigens to initiate adaptive immune response?
receptors | receptors combine with antigens
47
The adaptive immunity cells that are able to circulate between the blood, lymph, and peripheral tissues are the?
lymphocytes
48
lymphocytes with identical receptors are called?
clones | all cells in a clone respond only to a particular antigen
49
The cells that phagocytize foreign antigens are called? | these cells also insert antigens on their cell membranes w/ MHC class II
antigen presenting cells
50
this class of lymphocytes respond to MHC II and they **activate B cells and effector T cells**
Helper T cells
51
# True or False Helper T cells secrete cytokines that stimulate other immune cells.
True
52
Antibody-mediated immunity is most often stimulated by the activation of what lymphocyte? | Helper T or B cell?
Helper T cells | helper T stimulates B cells
52
Antibody-mediated immunity is most often stimulated by the activation of what lymphocyte? | Helper T or B cell?
Helper T cells | helper T stimulates B cells
53
CD4 cells are also known as?
Helper T cells
54
produced by helper T cells when presented with an antigen
Interleukin-2
55
the cells that produce antibodies are called?
plasma cells ## Footnote `
56
Stimulated B cells divide to form cells that secrete
antibodies
57
The region of an antibody molecule that binds to the antibody's target antigen is called the
variable region
58
The region of an antibody that can activate complement or bind to mast cells, macrophages, or basophils is the?
constant region | constant for complement activation; variable in antigen combination
59
four polypeptide chains of antibodies?
2 heavy; 2 light | identical w/ each other
60
The immune response that occurs after the first exposure to an antigen is referred to as the
primary immune response
61
memory B cells respond to an antigen during a ___ immune response
secondary immune response
62
# Immunoglobulin Identification **The majority of antibodies in the body are of this type.** It activates complement and is able to cross placenta. It is responsible for Rh reactions in newborns. | Gago May Aso Eto Daw
IgG
63
# Immunoglobulin Identification It **activates complement and functions as an antigen binding receptor** on the surface of B cells. It is **responsible for transfusion reactions in the ABO blood system** and is the first antibody type produced during a primary immune response.
IgM
64
# Immunoglobulin Identification It is found in saliva, tears, and mucous membranes, colostrum and milk. It also provides immune protection for newborns.
IgA
65
# Immunoglobulin Identification It binds to mast cells and basophils and stimulates inflammation.
IgE
66
# Immunoglobulin Identification It functions as an antigen-binding receptor on B cells.
IgD
67
What specific cell type is the effector cell for cell-mediated immunity (i.e., **the cell type that destroys the antigen-containing cell**)?
Cytotoxic T cell