Lysosome

Question 1

lysosome

Answer 1

• digestive organelle
• degrades all types of macromolecules

Question 2

autophagy

Answer 2

degredation of larger celluar components

Question 3

MGP receptor

Answer 3

in tGN soluable MPG bearing lysosomal destined proteins are recognized

Question 4

clathrin-coated transport vesicles

Answer 4

mGP receptor mediates lysosomal protein into it

Question 5

Apl anf GGA Adaptor coat proteins

Answer 5

• cytoplasmic facing domain of MGp receptor binds here
• mediate vesicle cargo
• linker for clathrun coat assembly

Question 6

Arf1

Answer 6

• recruit AP1/GGA
• binding of GTP causes conformatinal change
• bind tp clathrin

Question 7

triskeleton

Answer 7

• 3 legged structure of clathrin
• recruited from cytoplasm to form scaffolding

Question 8

scisison

Answer 8

• release of clathrin coated vesicle from TGN membrane
• mediated by dynamin ring (GTP dependent)

Question 9

YGTP

Answer 9

non hydrolyzable analpg pf GTP

Question 10

late endosomes

Answer 10

lysosomal cargo proteins that were pinched from tgn fuse to late endosomes

Question 11

retromer-coated vesicles

Answer 11

recycled empty m6P to TGN