Male Pathophysiology 1 Flashcards Preview

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Flashcards in Male Pathophysiology 1 Deck (30):
1

What are the most common congenital abnormalities of the penis?

Epispadias and hypospadias

2

What are epispadias and hypospadias

Abnormal openings of the urethra on the dorsal or ventral penis from malformation of the urethral canal.

3

Which is more common, Epispadias or hypospadias?

Hypospadias.

4

This notecard set is not going to be very thorough until the weekend of the 28th

ok

5

Inflammation of the penis

phimosis

6

Cryptorchidism

undescended testis

7

Penile duplication

Two urethral orifices

8

What is hypospadias

urethral opening on the bottom (ventral side of penis)

9

Phimosis

inability to easily retract the foreskin

10

Inflammation of the penis is generally due to phimosis or venereal disease

ok

11

Blanaitis=

glans inflammation

12

Posthitis

foreskin inflammation

13

phimosis

inability to retract the foreskin

14

What is a condyloma

warty, cauliflower like growths which occur primarily in the anogenital region, though you can get them wherever you have sex.

15

What HPV causes condyloma?

HPV 6 and 11

16

Squamous carcinoma in situ on the skin of the penis is called?

Bowen disease

17

Squamous carcinoma on the glans of the penis

erythroplasia of queryat.

18

80% of penile dysplasias are related to what?

HPV...usually type 16. If left untreated, will progress to squamous cell carcinoma

19

Squamous cell carcinoma of the penis is related to HPV 50% of the time (types 16 and 18). Other risk factors include smoking and poor hygiene

ok

20

cryptorchidism

undescended testes

21

Klinefelter syndrome

Too many x chromosomes....usually xxy

22

Eunuchoid appearance

Increased stature, small to normal sized well developed testis
- incomplete virilization
- gynecomastia
- mental retardation

23

Histology of Klinefelter seminiferous tubules

small hyalnized

24

What is distinct about the Leydig cell layout in Klinefelter?

Psuedoadenomatous clusters of Leydig cells. Just appear this way because of decreased testicular volume. There is really no increase in number

25

Klinefelters patients are at risk for increased incidence of extragonadal germ cell tumors and hypopituitarism

ok

26

Focal atrophy of the testicular tubules

Mumps Orchitis

27

What is testicular torsion

twisting of the spermatic cord leading to ischemia and venous stasis,
May be related to trauma but often the inciting event is obscure.
Surgery within 4-6 hours may save the testis; after that, infarction will obliterate it.

28

Hypospadias is caused by?

Failure of the urethral folds to close

29

Epispadias caused by

Abnormal positioning of the genital tubercle

30

Bowen Disease

In Situ Carcinoma of the penile shaft or scrotal skin, presents as leukoplakia. This is a precursor for squamous cell carcinoma of the penis