Male Repro Flashcards

(50 cards)

1
Q

3 Subprocesses of Spermatogenesis

A

Spermatocytogenesis
Meiosis
Spermiogenesis

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2
Q

Hormones for Sperm Production and Maintenance (4) (and functions)

A

LH (stimulates Leydigs to produce testosterone)
FSH - stimulates Sertoli cells which stimulate androgen-binding protein to maintain high T levels in testes
Testosterone -
Inhibin - feedback to inhibit LH and FSH production

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3
Q

Intratesticular Path of Sperm Transport (4)

A

Seminiferous tubules - tubuli recti - rete testis - ductuli efferentes

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4
Q

Tubuli Recti

A

Straight tubules at end of each of coiled seminiferous tubules

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5
Q

Rete Testis

A

Network of cuboidally-lined vessels that mix sperm together

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6
Q

Ductuli Efferentes

A

Efferent ductules to leave testis and go into epididymus

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7
Q

Extratesticular Path of Sperm Transport (4)

A

Ductus epididymis
Ductus deferens
Ejaculatory duct
Urethra

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8
Q

2 Producers of Semen Components for Maintenance

A

Seminal vesicles and prostate

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9
Q

Two Layers of Testes Capsule (and composition)

A

Tunica albuginea - DIRCT thick outer capsule

Tunica vasculosa - vascular layer w/ loose connective tissue

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10
Q

Germinal Epithelium

A

Just deep to tunica vasculosa, is unique because has layers of developing sperm but also Sertoli cell which spans the whole thing (basement to lumen)

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11
Q

Tunica propria

A

In between the tubules, which has collagen and such

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12
Q

Spermatocytogenesis

A

Mitotically dividing spermatogonia to make more

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13
Q

2 Types of Spermatocytogenesis

A

Type A - produce more spermatogonia

Type B - produce primary spermatocytes moving into spermatic cycle

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14
Q

Direction of Sperm Formation

A

Begins in periphery, moves towards center lumen

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15
Q

3 Spermatic Phases in Meiosis (& chrom/N number)

A

Primary Spermatocytes - 46 Chromosomes, 4N
Secondary Spermatocytes - 23 Chromosomes, 2N
Spermatids - 23 Chromosomes, N

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16
Q

Spermiogenesis

A

Morphologically change haploid spermatid

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17
Q

3 Phases of Spermiogenesis (and what they are)

A

Golgi phase - makes acrosomal enzymes
Acrosomal phase - once acrosome is formed
Maturation phase - really changes morphology

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18
Q

Residual bodies

A

cytoplasm shed off during spermiogenesis, taken up and recycled

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19
Q

5 Sections of Sperm

A

Head w/ acrosome and DNA, neck, middle piece w/ mt, principal piece, and end piece

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20
Q

Spermiogenesis Nucleus Trend

A

Goes from euchromatic to heterochromatic, so limited lifespan

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21
Q

Total Time of Sperm Production

22
Q

Cytoplasmic Bridges

A

Between sperm precursors in sperm production, transfer prots from X chrom-containing units to Y-containing, last until residual bodies

23
Q

Sertoli Cells (6)

A
Supporting, nurse cells
Extend throughout germinal epithelium
Support/protect developing sperm
Phagocytosis of residual bodies
Synthesize ABP and inhibin
Form blood-testis barrier via occluding junctions between them
24
Q

5 Items in Interstitial Tissue in Testes

A

Nerves, blood vessels (fenestrated capillaries), lymphatics, connective tissue, and Leydig cells

25
Androgen-Binding Protein
Produced by sertoli cells, binds diffusing testosterone and keeps it in seminiferous tubules bathing the area
26
Countercurrent Heat Exchanger
Pampinform plexus cools testicular a. about 2 degrees cooler
27
Tubuli recti epithelium
Cuboidal
28
Ductus efferentes epithelium (3)
Ciliated (to beat sperm to epididymus) and non-ciliated cuboidal and columnar
29
Ductus Epididymus
One long coiled duct where sperm are stored
30
Walls of Ductus Epididymus (2)
Pseudostratified columnar epithelium w/ stereocilia surrounded by smooth muscle for peristalsis
31
Stereocilia
Not cilia, actually microvilli to increase absorption SA to suck out water to concentrate sperm and act as vacuum
32
Ductus Deferens Wall (3.3)
Pseudostratified columnar epithelia w/ stereocilia Lamina propria w/ elastic fibers Thick muscular wall (inner longitudinal, middle circular, outer longitudinal)
33
Ampulla
Dilation of ductus deferens prior to prostate
34
Distinction Between Ureter and Ductus Deferens (2)
Ureter only has a few layers of smooth muscle instead of really thick wall Ureter has transitional epithelium, not pseudostratified columnar
35
Ejaculatory Duct Epithelium
Simple columnar epithelium
36
Seminal Vesicles Epithelium
Pseudostratified columnar epithelium
37
Seminal Vesicles Lamina Propria
Elastic fibers and fibroblasts
38
Seminal Vesicles Product
70% of seminal fluid, w/ fructose and citrate
39
Prostate Product
Produces thin white fluid w/ acid phosphatase which stimulates motility and changes vaginal pH
40
Prostate Epithelium (3)
Simple cuboidal and columnar epithelium (some pseudostratified)
41
Prostate Stroma (2)
Fibromuscular: smooth muscle and elastic fibers
42
Corpa Amylacea
Prostatic concretions
43
Bulbourethral (Cowper's) Glands
Release mucous secretion to lubricate urethra prior to ejaculation
44
Kartagener's Syndrome Effect on Male Repro
Sperm will be immotile, infertilitiy
45
Cryptorchidism
Testes inside body, nonfunctional sperm if untreated
46
Varicocele
Torsion of testicle, can torque vessels and prevent bloodflow
47
Testicular Autoimmunity
If tight junctions b/w Sertoli cells lost, Abs can attack own sperm
48
Prostatic Hypertrophy
Prevents flow of urine through urethra, possibly caused by cancer on posterior side of prostate
49
Testicular Tumors
Can metastasize back to abdomen via lymphatics
50
PSA
Prostate something antigen, controversial measure of prostate cancer likelihood