metabolic Flashcards
(48 cards)
physiological cuase of raised ALP
preg
ALP can also be raised in
bone mets
ezetimibe mechanism of action
lipid lowering
ezetimibe used
statin not working
primary heterozyous familial
familail hypercholesterolaemia affects what cholesterol
LDL - the bad one
tendon xanthoma suggests
familial hypercholesterolaemia
when should statins. be stopped beffore conception
3 montsh
children of affected pts with familail hypercholesteroalemai
if one parent affected - arrange testing by age 10
if both paretns affect - arrange testing by age 5
high glycaemic index means
ability to raise blood glucose compared to other
inital mx of hypercalcaemia
saline
how long do biphosphoantes take to work
2-3 days with maximal effect at 7 dyas
drug that has a quicker effect than biphosphoante
calcitonin
– such as furosemide are sometimes used in hypercalcaemia, particularly in patients who cannot tolerate aggressive fluid rehydration. However, they should be used with caution as they may worsen electrolyte derangement and volume depletion.
loop diuretics
unusual things that can cuase hyperkaamia
beta blcoekrs in renal failure pts
heparin
when to not use QRISK for assessing risk for statins as there is more specific guidelines for these
type1
egfr less than 60
hx familial hyperlipidaemia
when to consider familail hypercholesterolaemia
total choesterol greater than 7.5 and history of premature coronary heart disease = event before 60
all people with CKD should be started on what dose statin
20mg if not increased by 40% and egfr over 30 incerase dose, if egfr less than 30 consulat renal specialist
all pts with established cardiovasculr siease eg stroke, ischameic heart disease should take
high dose statin regrdless of baseline lipid profiel
exercise should
150mins moderate
75 mins vigorous
2 strength training
acute pancreatitis may cause
hypocalcaemia
why better to give IV calcium glcuoante as posoite to Iv calcium chlroide
chloride is more liekly to cause local irritation
carpopedal spasm in hypocacalmia referrs to
painful contractin s of muscles in hands and feet
cushing and conns asscoaited with
hypoakalemia
causes of pseudo low sodium
high lipids
taking blood from a drip arm
