Metabolic bone

Question 0

Osteoporosis labs

Answer 0

normla

Question 1

Osteoporosis common fx sites?

Answer 1

Vertebrae
hip
wrist

Question 2

Osteoporosis types

Answer 2

Primary- type I Menopause, Type II senile (renal production of vit D)
Secondary

Question 3

DEXA- severities, recommendations

Answer 3

Osteopenia 1-2.5SD

women over 65

Question 4

BMD

Answer 4

bone mineral density

DEXA scan measures

Question 5

FRAX score

Answer 5

osteoporosis

10yr fx risk

Question 6

risk factors for osteoporosis

Answer 6

alcoholism, sedentary lifestyle, smoking, corticosteroids

Question 7

Osteoporosis pharmacotherapy

Answer 7

anti-resoprtives (BP, SERM, hormones, calcitonin)
anabolic agents (PTH)
monoclonal antibodies

Question 8

Osteomalacia labs

Answer 8

low Ca, low P, low vit D, high PTH

Question 9

Osteomalacia types

Answer 9

I- alpha hydrolase deficiency –> limited vit D active form

II- hereditary vit D receptor failure –> limited Ca absorbed

Question 10

Paget’s disease (AKA)- epidemiology

Answer 10

Osteitis deformans- high turnover

male, european (possible viral origin)

Question 11

Paget’s disease labs

Answer 11

high alkaline phosphatase

Question 12

Paget’s diisease radiograph

Answer 12

wooly appearance, sclerosis, bowing

Question 13

Paget’s disease diagnosis w?

Answer 13

bone scan, bone biopsy

Question 14

Paget’s disease clinical features

Answer 14

high vascularization –> cardiac failure
warmth
increased head diameter, bone pain

Question 15

Paget’s disease treatment

Answer 15

BP

calcitonin