Microbial diseases: nervous system Flashcards

(40 cards)

1
Q

What are the three membranes of the spinal cord and brain called?

A

Meninges

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2
Q

What is the outside layer called?

A

Dura mater

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3
Q

What is the middle membrane called?

A

Arachnoid mater

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4
Q

What two spaces are found between the arachnoid mater and pia mater?

A

Subarachnoid space and Cerebral fluid (CSF)

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5
Q

Inner membrane?

A

Pia mater

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6
Q

how many ml of CSF are in between the arachnoid mater and pia?

A

100-150… I think

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7
Q

What is the blood brain barrier?

A

Certain capillaries permit some substances to pass from the blood into the brain (Restricts others)

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8
Q

What alters the permeability of the blood brain barrier?

A

Inflammation

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9
Q

What is meningitis?

A

inflammation of the meninges

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10
Q

What is encephalitis?

A

Inflammation of the brain

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11
Q

What passes the BBB?

A

Lipid soluble drugs and small molecules

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12
Q

DO you have a fever with both meningitis and encephalitis?

A

Yes

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13
Q

Do you have a headache, nausea, vomiting, and lethargy with both meningitis and encephalitis?

A

Yes

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14
Q

Do you have photophobia and neck stiffness with both meningitis and encephalitis?

A

Just meningitis

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15
Q

Why is pathogenic bacteria so serious?

A

Bacterial infections can have fatal consequences in the brain and spinal cord (lack of complement)

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16
Q

What can meningitis be caused by?

A

Bacteria, viruses, fungi, and protozoa

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17
Q

Is viral meningitis more common?

18
Q

Is viral meningitis more mild or severe?

19
Q

When does viral meningitis mostly occur?

A

Summer and fall months

20
Q

Where are enteroviruses found in the body that causes viral meningitis?

A

Throat and intestinal tract

21
Q

_____ _______: capsule: protects from phagocytosis( replicates rapidly)

A

Bacteria pathogens

22
Q

_____ ______: Release cell wall fragments

A

Bacteria pathogens

23
Q

_____ ______: Patients die from shock or inflammation

A

Bacteria pathogens

24
Q

_____ ______: Patients die from shock or inflammation

A

Bacteria pathogens

25
Bacterial meningitis is caused by which species of streptococcus?
Streptococcus pneumonia
26
S. pneumonia is gram....
positive
27
S. pneumonia is a ____coccus
diplococcus
28
Is S. pneumonia encapsulated?
Yes
29
_____ ______ is the leading cause of meningitis
S. pneumonia
30
What percent of the population are healthy carriers for S. pneumonia?
70%
31
IS there an effective vaccine?
Yes, conjugate vx available for infants under the age of 2
32
Which species of neisseria causes meningitis?
Neisseria meningitidis
33
Is Neisseria meningitidis gram + or -
Negative
34
What percent of the population are reservoirs for N.M
40%
35
Transmission of N.M?
Droplet or direct contact
36
Why are there sporadic outbreaks of N.M meningitis in college students?
Lack of contamination, sexual contact, etc
37
What is the vaccine for NM called?
MenB (bacterial surface protein)
38
NM occurs mainly in.....
children less than 2 (causes residual damage)
39
Which species of Listeria causes meningitis?
Monocytogenes
40
What species of Haemophilus causes meningitis?
influenza type B (HIB)