Microbiology Gram Negative Bacterial Diseases

Question 1

Gm negative have cell walls?

Answer 1

yes

Question 2

What are our gram negative Cocci

Answer 2

Neisseria Meningitidis

N. Gonorrhoeae

Question 3

Gram negavtive coccoid rods

Answer 3

H. Influenzae

Bordetella Pertussis

Question 4

Oxidase positive comma shapped that crows in 42 degrees celcius

Answer 4

Campylobacter Jejuni

Question 5

Oxidase positive that grows in alkaline media

Answer 5

vibrio cholerae

Question 6

What are our gm - rods that are lactose fermentors

Answer 6

Klebsiella

E.coli

Question 7

What are the gram negative rods that do not ferment lactose

Answer 7

Pseudomonas
Shigella
Salmonella
Proteus

Question 8

What gm - rods are oxidase positive

Answer 8

Psudomonas

Question 9

What Gm- rods are oxidase negative

Answer 9

Shigella
Salmonella
Proteus

Question 10

What are the virulence factors of neisseria

Answer 10

FImbria
Capsule
Protease (inhibit IgA)
Lipid A endotoxin
Oxidase positive

Question 11

What does it mean to be oxidase positive

Answer 11

use oxygen from ETC = aerobe

Question 12

What enviornment does neisseria thrive in

Answer 12

CO2 rich

Question 13

Neisseria meningitidis has what virulence factors

Answer 13

Capsule made of N-acetylneuramininic acid

LOS: lipid A

Question 14

What diseases does niesseria meningitidis cause and in what demographic

Answer 14

Meningitis

Septicemia/death

Question 15

Where can neisseria gonorrhoeae replicate

Answer 15

In WBC’s

Question 16

What diseases does N. gonorrhoeae cause

Answer 16

STI
Septic Arthritis
PID
Neonatal conjunctivitis

Question 17

What type of medium do you grow Neisseria on

Answer 17

Chocolate and Thayer-Martin

Question 18

What are the main characteristics of Klebsiella pneumoniae

Answer 18

• It is a fast lactose fermentor
• capsule (quelling reaction) swelling

-Mostly Nosocomial

Question 19

Diseases that Klebsiella causes

Answer 19

• UTI (hospital acquired)

- Pneumonia (diabetic, alcoholic)

Question 20

Red current jelly sputum is what organism

Answer 20

Klebsiella

Question 21

What is the main type of entero hemorrhagic E. Coli

Answer 21

0157:H7

Question 22

What are the main pathogenicities for E. coli

Answer 22

Plasmids
Shiga like toxin
Type III secretion system

Question 23

What syndrome can E.coli cause

Answer 23

Hemolytic Uremia Syndrome

Question 24

What are the main characteristics of Shigella

Answer 24

-Nonmotile
Cell to Cell transmission
Doesnt Ferment Lactose
Urease and Oxidase negative

Question 25

What are the 4 F's and what bug are they associated with

Answer 25

Food, Finger, Feces, Flies Shigella

Question 26

What toxin and what disease does shigella cause

Answer 26

has endotoxin and Exotoxin: Shiga toxin Watery bloody mucuousy didysentery

Question 27

What is the main characteristics of salmonella

Answer 27

Motile | Urease and oxidase negative

Question 28

What is the main sequella of Salmonella

Answer 28

Typhoid fever from S. typhi Gastroenteritis, bactermeia, peritonitis

Question 29

Rose spots on abdomen, Fever, headache, diarrhea or constipation think

Answer 29

typhoid fever

Question 30

What type of E. coli has LT (heat labile) and ST(heat stable) proteins

Answer 30

Enterotoxigenic (ETEC)

Question 31

what are the main characteristics of preoteus

Answer 31

Urease Positive Oxidase negative Flagella make it very motile

Question 32

What two diseases do proteus cause

Answer 32

UTI | Kidney Stones

Question 33

Why does urease lead to kidney stones

Answer 33

takes acid and makes base (ammonia) leads to struvite stones

Question 34

Main characteristics of Pseudomonads

Answer 34

Oxidase Positive Produces Blue-green pigment Grape like odor

Question 35

Diseases pseudomonads cause

Answer 35

- Wound and burn infections | - Hot tub foliculitis

Question 36

What diseases does Pseudomonas aeruginosa cause

Answer 36

-Pneumonia: cystic fibrosis patients and immunocompromised Ostemyelitis: dibetetic and IV drugs - Burn wound infections - UTI/pylo in nursing home hospital aquired - Endocarditits in IV drug users

Question 37

What are the two types of cocobacillus describe them

Answer 37

Haemophilus and bordetella Shape between rod and cocci Anerobic

Question 38

What is the main pathogeniciy of Haemophilus Influenzae

Answer 38

- Capsule B= bad | - IgA protease

Question 39

What diesaes does Haemophilis influenzae cause

Answer 39

-Meningitis -Epiglottitis Oneumonia

Question 40

What does Haemophilis ducreyi cause

Answer 40

painful genitial ulcer (chanchroid) Painful inguinal lymphadenopathy

Question 41

What is the epidemiology and pathogenicity of bordetella

Answer 41

Inhibits ciliary action Adhesins Toxins

Question 42

What are the toxins of bordetella

Answer 42

Pertussis adenylate cyclase dermonecrotic tracheal

Question 43

what type of culture do you grow bordetella in

Answer 43

regan-lowe agar

Question 44

what are the three stages of whooping cough

Answer 44

- Catarrhal stage (non descript URI) - Paryoxysmal stage ( non productive cough with whoop, vomiting cyanosis) - Convalescent stage (less severe persistent cough)