Mid 2: Lec 12 Flashcards
(5 cards)
1
Q
SREBP 2
A
regulates cholesterol biosynth
2
Q
ppars
A
nuclear hormone receptors
regulate cellular lipids and cholesterol levels
3
Q
mir 27
A
regulate TAG and cholesterol
4
Q
HCV and miR27
A
HCV induces miR-27 expression
results in TG accumalation (steatosis) in liver
miR-27 overexpression inhibits HCV
replication
5
Q
ppar and mir 27 TG
A
PPAR-α agonism reverse miR-27
mediated TG accumulation
