Miscellaneous enzymes Flashcards

1
Q

A phosphoric monoester hydrolase

A

Nucleotidase (5’N)

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2
Q
  • Predominantly found in the liver
  • Marker for the hepatobiliary and infiltrative lesions of the liver
A

Nucleotidase

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3
Q

T/F: Nucleotidase can also serve as liver enzyme marker

A

TRUE

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4
Q
  • Index of parenchymal function
  • Used to monitor the effect of muscle relaxants (succinylcholine) after surgery
A

Cholinesterase / Pseudocholinesterase

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5
Q

Marker for insecticide or pesticide poisoning (organophosphate)

A

Cholinesterase / Pseudocholinesterase

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6
Q

Angiotensin-Converting Enzyme is also known as

A

Peptidyldipeptidase A or Kininase II

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7
Q

The active form for angiotensin

A

Angiotensin 2

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8
Q

Increase ACE is seen on

A

Sarcoidosis, acute and chronic bronchitis, and leprosy

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9
Q

Main source of ACE

A

Macrophage and Epithelioid cells

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10
Q

A protein carrying the copper in the plasma

A

Ceruloplasmin

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11
Q

Marker for Wilson’s dse (hepatolenticular dse)

A

Ceruloplasmin

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12
Q

For hepatobiliary dse

A

Ornithine Carbamoyl Transferase (OCT)

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13
Q

Important to maintain NADPH in the reduced form in the erythrocyte

A

G6PD

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14
Q

Stabilizes cell membrane and protect it from lysis

A

NADPH

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15
Q

Measure among babies (A newborn screening marker)

A

G6PD

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16
Q

G6PD is seen on what organs?

A

Adrenal cortex, spleen, RBC, and lymph nodes

17
Q

Deficiency can lead to drug-induced hemolytic anemia (primaquine, antimalaria drug)

A

G6PD

18
Q

Increased G6PD is seen on

A

MI, Megaloblastic anemia