mod 3- info

Question 1

energy yield from betahydroxybuterate and acetoacetate

Answer 1

beta- 21.5 atp

acetoacetate- 19.5

Question 2

what is diabetic ketoacidosis and what causes it

Answer 2

excess buildup of keytone bodies in blood of type 1 diabetic patients

• if insulin inj is missed
• Fa mob is triggered causing large ammount of keytones to be released

Question 3

how many atp used for Fa SYNTHESIS

Answer 3

2atp

Question 4

how much manonyle coa and acytle coa is utalized to make FAs

Answer 4

7 manonyl coa

1 acytle coa

Question 5

what are the 2 sources of NADH for

Answer 5

1. Malic enzyme

2. Pentose-phosphate pathway

Question 6

How does CPT1 influence Fa synthesis

Answer 6

• is responsible for transporting acyl coa thru mito membrane
• is inhibited by malonyl coa (which is produced in fed state)-

Question 7

what are the 2 essential fas

Answer 7

Archindoic + linoleic acid

Question 8

what are 2 other Fas

Answer 8

Steorate

Oliec

Question 9

what are the peripheral pros on VLDLs + what do they do

Answer 9

apob100- allows liver to recognize it as molecule that needs to be released

ApoC- allows lipopro lipase to recognize VLDL and cut it

Apo E- allows liver to recognize + take up VLDL remenent has been broken down

Question 10

where is FA synthesis loacated

Answer 10

cytoplasm

Question 11

cholesterol functions (4)

Answer 11

1. Bile acid synthesis (in liver)
2. cholesterol esterfication (makes more hydrophobic)
3. Steroid synthesis
4. Vit D formation

Question 12

makeup of chylomicrons

Answer 12

TG
Cholesterol
Cholesterol Ester
Peripheral + integral pro (APoA)