Module 11 Exam 4 Flashcards

(66 cards)

1
Q

What do bacteriocidal antibiotics do

A

inhibit bacterial cell wall sythesis

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2
Q

What antimicrobials are bacteriocidal and have a beta lactam ring

A

penicillin

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3
Q

What are narrow spectrum antibiotics effective agains

A

gram negative bacteria

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4
Q

what are broad spectrum atnibiotics effetive against

A

gram - and gram +

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5
Q

What characterizes a gram + bacteria

A

increased peptidogycan in cell wall and lack outer membrane

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6
Q

Why do we get penicillin resistance

A

bacterial resistance against beta lactam riing

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7
Q

what does the beta lactam ring do

A

interferes with bacterial cell wall synthesis

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8
Q

what is done to combat penicillin resistance

A

add a clavulanate to restore its effectiveness

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9
Q

What are 2 mecications that were made to combat penicillin resistance

A
  • Augmentin (amox+claulanate) ORall

- Timentin (ticarcillin+cal) IV

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10
Q

What is the prototype for natural penicillin

A

Penicillin G

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11
Q

What are the narrow spectrum (natural) antimicrobials

A
Penicillin V*
Penicillin G (inj)
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12
Q

What are some qualities about narrow specturm antiboitics

A
  • bacteriocidal
  • yogurt
  • cause fungal overgrowth
  • protect esophagus
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13
Q

What are some examples of broad spectrum antibacterials

A

amoxicillin (Amoxil, Trimox)*

ampicillin

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14
Q

What have a possible interacton with oral contraceptives

A

broad spectrum antibacterials

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15
Q

What is a beta lacamase inhibitor

A

Augmentin*

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16
Q

What is penicillin VK prescribed for

A

moderate endo, perio or odonto abcess, NUG

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17
Q

What is amoxicillin prescribed for

A

skin infection, sinusitis, and bite woulnds

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18
Q

what is augmentin prescribed for

A

aggressive forms of infection

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19
Q

What are cephalosporins

A
  • broader range then penicillin

- interfere with bacterial cell wall synthesis

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20
Q

What is a first generation cephalosporin

A

-Keflex, gram + *

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21
Q

What is a second generation cephalosporin

A

Gram - & +

ceclor*

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22
Q

what is a third generation cephalosporin

A

Rocephin mixed with Lido*

greater range of gram -

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23
Q

What is the fouth generation cephalosporin

A

tx or MRSA

Maxipime*

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24
Q

What can and cant cephalosporins be uesd for

A

can: premed
cant: endo and perio abcess

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25
What are effective against strict anaerobic bacteria
nitroimadazoles
26
what is the dental med used of nitroimadazoles
Flagyl
27
what needs to be avoided in the use of Flagyl
alohol, mouthrinses
28
what are nitroimadazoles used to treat
NUG, aggressive forms of perio, Endo, peri-implant infectons
29
What are quinilones used for
bacteriocidal, broad spectrum anti microbial
30
What are two examples of Quinolones
* cipro | * Levaquin
31
What is utilized when a patient is allergic to penicillin
erythromycin
32
What macrolide is used when pt has strep, penumonia, middle ear inf
Zithromax
33
what macrolide is used when a patien has pharyngitis, tonsillitis, sinusitis
Biaxin
34
What is a macrolide
bacteriostatic similar to erythromiycin
35
What is a tetracyline
bacteriostatic and broad spectrum
36
How do tetracyclines affect host response
ihibits production and secretion of collagenase by PMNS
37
What makes up the conn tissue of the peiodontium
collagen
38
What are 2 medications that tetracyclines
doxycyline* Periostat*
39
What medications exhibit high concentrations in the creviclar fluied
tetracyclines
40
What are some problems with tetracycline
photosensitivy, stain, dont take with milk
41
What are the most common causes of anaphylactic death
penicillin, bee stings, wasp stings
42
What is an allergic reaction a result of
immunologic reaction to noninfectious foreigh substance
43
What happens with a repeated contact with an antigen
hypersensitiviy hestructive to host tissue cellular and humoral components
44
What is the primary lymphocyte in humoral immunity
B lymphocyte
45
What remain inactive until they come in conact wtih the same type of antigen
b memory cells
46
What immune system is involved in Type 1 hypersensitivity
humoral
47
When dose type 1 hypersensitivy occur
after the second contact (may have several exposures)
48
What does histamine relase cause
smooth muscle contraction | increases permeability vasculature
49
What is the most serious type of allergic response
anaphylaxis
50
What is anaphylaxis usually caused by
parabens | sulfites
51
What are other type 1 hypersensitivity reactions
``` hay fever asthma urticaria dust mites pollen dander food-drugs ```
52
What are the most common food allergies of Type 1
shellfish, nuts, eggs, milk
53
what are the most comon insect allergies of type 1
bees, wasps, hornets, yellow jackets
54
What are the drugs that cause a type 1 hypersensitivity
penicillin sulfa NSAIDS
55
does codeine usually cause a true allergic response
no
56
What are the signs and symptoms of allergic reactions
itching, vomiting, aarythmias, hypotension, Bronchoaspasm
57
What are medications used in an allergic reaction
- H1 receptor antagonists - Intaranasal glucocorticoids - sympathomimetics
58
What are examples of first generation h1-receptor antagonists
Benadryl *
59
what are examples of second generation H1-receptor antagonists
zyrtec * Allegra * Claritin *
60
What are examples of intranasal gulocorticoids
Rhinocort* FLonase* Nasonex*
61
What is the celluar immune system sometimes referred to as
delayed immune system
62
what plays a signigicant roll in the celluar immune system
T-lympocytes
63
What do Memory T cells do
remember the antigen for years
64
What allergens cause contact dematitis
nickel, latex, amaglgam
65
What is the treatment of cellular immune reactions
remove material causing rxn, most are self limiting and dont require additional tx
66
what reactoins is the celluar immune system responsible for
- concact dermatitis graft rejections some drug hypersensitivity some autoimmune diseases