Module 2E Flashcards

(32 cards)

1
Q

nucleic acids

A

macromolecules composed of polymers called polynucleotides

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2
Q

what is each polynucleotide made of

A

monomers called nucleotides

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3
Q

examples of nucleic acids

A

DNA and RNA

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4
Q

nucleotides

A

building blocks of polynucleotides consisting of a 5 carbon sugar, a nitrogen-containing base, and one to three phosphate groups

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5
Q

what is the structures of double stranded DNA or single stranded RNA is dependent on

A

hydrogen bonding that forms base pairs

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6
Q

trasnfer RNA

A

transport amino acids from cytoplasm to ribosome

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7
Q

does trasnfer RNA contain double helix

A

no

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8
Q

what does deoxy mean

A

lacking oxygen

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9
Q

phosphodiester bond

A

covalent link between phosphate group and sugars of two nucleotides

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10
Q

what is the major difference between RNA and DNA

A

hydroxyl group on 2 prime carbon in RNA and Uracil instead of Thymine

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11
Q

how do double helix, the two backbones run

A

in opposite 5’->3’ directions from each other (anti parallel)

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12
Q

A binds to

A

T (uracil)

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13
Q

C binds to

A

G

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14
Q

gene

A

amino acid sequence of polypeptides by a unit of inheritance

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15
Q

mRNA

A

single-stranded molecule of RNA that corresponds to the genetic sequence of a gene and is read by ribosomes in the process of synthesizing a protein

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16
Q

who reported DNA composition in 1950

A

Erwin Chargaff

17
Q

who produced a pcitrue of the DNA molceule using x-ray crytallography

A

Rosalin Franklin

18
Q

X-ray crystallography

A

determines molecular structure of a crystal by hitting the crystal with x-rays and seeing how the x-rays diffract

19
Q

what did James watson do

A

built a model in which the backbones were antiparallel

20
Q

Is DNA uniformed in width

A

yes, purine and pyrimidine widths is consistent with X-ray data

21
Q

what helps stabilize DNA

A

short distance between bases

22
Q

DNA is how narrow and how long

A

very and very

23
Q

what is DNA in eukaryotes wrapped around in and what does it form

A

wrapped around histone proteins to form condensed chromosomes

24
Q

who was the first black women to earn a PhD in chemistry in the US in 1947

25
semiconservative model
Replication predicts that each daughter molecule will have one old strand (conserved from the parent molecule) and one newly made strand
26
helicase
opens up the double strand
27
DNA polymerase
catalyzes synthesis of new DNA at a replication fork
28
leading/lagging strands
are new complimentary strand (5'->3')
29
what does "ase" at the end of a word indicate
enzyme
30
what are RNA primers used for
to initiate the synthesis. of both the leading and lagging strands
31
what does DNA ligase do
removes primers and seals the DNA together
32
mutations are a source of
genetic variation upon which natural selection operates and are ultimately responsible for the appearance of new species