Module 7 Wk 2 Flashcards
(236 cards)
what produces the matix in cartlidge?
chrondroblasts
what maintains matrix in cartilidge?
chrondrocytes
what does ECM consist of in cartilidge?
fibres for rigidty
ground substances for resiliencyw
what does the fibre depends on within cartilidge?
what type of cartilidge
what does avascular mean?
no blood supply
what are the 3 types of cartilidge
- hyaline
- fibrocartilidge
-elastic cartilidge
what is the most commen type of cartilidge?
hyaline
what does hyaline cartilidge form?
temp skeleton in embryo which is gradually replaced by bone (long bones)
what is hyaline cartilidge made from?
u- abundent ground substance plus a few type 2 collogen fibres
where would you find hyaline cartilidge in adults?
articulating surface of moveable joints, walls of resp passages , costal cartilidge
T/F hyaline cartilidge goes underboth appositional and interstitial growth
True
what is elasatic cartilidge characterised by?
The precence of abundanct elastic fibres and is quite cellular
Where other than the ear pinna is elastic cartilidge found?
epiglottis
What is Fibro-cartilidge distinguished by?
It’s high content and orderly arrangement of type 1 collagen fibers.
Where is Fibro-cartilage typically found?
Regions where tendons attach to bones, the invertrbral discs and the symphysis between certain bones.
T/F there is lots of ground substance in Fibro-cartilage?
False - Limited
How are the cells arranaged in Fibro cartilage?
Chondricytes and Chondroblasts arranged in colums between bundles of collagen fibres.
What 2 types of cartlidge have appositional growth?
- hyaline
- elastic
Describe appositional growth?
New cartilidge forms at the edges
- Fibroblasts differentiate to chondroblasts and synthesise artilidge ECM
- Chondrocytes maintain the ECM
Describe Intersitial growth?
Growth within existing cartilage
- Chondrocytes become reactivated to blast form
- Then undergo cellular division to form isogenous groups that produce additional ECM
What is the function of synovial fluid apart from nurtrition?
Lubrication - provides film on cartilidge seeping in via mechanical action. Once seeped in it can go into spongey bit where it will dampen the effect of imapction
What is a sign using synovail fluid that there is problem in or around the joint?
- cloudy fluid
- blood in it
In cartilage, what is the main cell type involved in the formation of the extracellular matrix?
Chondro blasts
In cartilage which type of growth gives rise to the formation of isogenous groups?
Intersitail growth