Module Three, Lecture Twenty Nine Flashcards
Homeostasis of Plasma Glucose and Diabetes Mellitus (10 cards)
What is the importance of Plasma Glucose Homeostasis?
Ensures a constant supply of energy to vital organs e.g. the brain
What is the reference range for Plasma Glucose Concentration? ( 2 )
- 3.5 - 6 mmol/L Fasting
- 3.5 - 8 mmol/L Non-Fasting
Why is blood glucose concentration so important? ( 2 )
- Brain cells are largely dependent on glucose as an energy source
- Other cells are better able to use alternative substrates for ATP production when glucose levels are low
What do prolonged high glucose blood levels result in? ( 5 )
- Cardiovascular disease
- Nerve Damage
- Kidney Damage
- Vision problems
- Foot Problems
Where is the Pancreas located?
In the curve of duodenum and consists of head, body and tail
What are some functions of the Pancreas? ( 4 )
- Assisting with digestion
- Regulating blood sugar levels
- Produces digestive enzymes that break down food
- Releases hormones like insulin and glucagon to control blood glucose
What are Alpha cells and their function?
Specialised cells within the pancreas that produce and secrete the hormone glucagon. Increases Blood Glucose Levels
What are Beta Cells and their function?
Specialised cells in the pancreas responsible for producing and releasing the hormone insulin. Reduces Blood Glucose Levels
What is Insulin?
Protein hormone synthesised on rER of beta cells. Insulin corrects hyperglycemia by facilitating glucose uptake into cells of most body tissues