Module Three, Lecture Twenty Nine Flashcards

Homeostasis of Plasma Glucose and Diabetes Mellitus (10 cards)

1
Q

What is the importance of Plasma Glucose Homeostasis?

A

Ensures a constant supply of energy to vital organs e.g. the brain

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2
Q

What is the reference range for Plasma Glucose Concentration? ( 2 )

A
  1. 3.5 - 6 mmol/L Fasting
  2. 3.5 - 8 mmol/L Non-Fasting
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3
Q

Why is blood glucose concentration so important? ( 2 )

A
  1. Brain cells are largely dependent on glucose as an energy source
  2. Other cells are better able to use alternative substrates for ATP production when glucose levels are low
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4
Q

What do prolonged high glucose blood levels result in? ( 5 )

A
  1. Cardiovascular disease
  2. Nerve Damage
  3. Kidney Damage
  4. Vision problems
  5. Foot Problems
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5
Q

Where is the Pancreas located?

A

In the curve of duodenum and consists of head, body and tail

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6
Q

What are some functions of the Pancreas? ( 4 )

A
  1. Assisting with digestion
  2. Regulating blood sugar levels
  3. Produces digestive enzymes that break down food
  4. Releases hormones like insulin and glucagon to control blood glucose
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7
Q

What are Alpha cells and their function?

A

Specialised cells within the pancreas that produce and secrete the hormone glucagon. Increases Blood Glucose Levels

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8
Q

What are Beta Cells and their function?

A

Specialised cells in the pancreas responsible for producing and releasing the hormone insulin. Reduces Blood Glucose Levels

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9
Q

What is Insulin?

A

Protein hormone synthesised on rER of beta cells. Insulin corrects hyperglycemia by facilitating glucose uptake into cells of most body tissues

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10
Q
A
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