MOLECULAR DISPERSIONS Flashcards
(39 cards)
dispersed phase completely dissolved – homogenuous molecular dispersion
TRUE SOLUTION
particle size of true solution
below 1nm
can’t scatter light and can’t be visualize using the microscope
TRUE SOLUTION
Multi-component – mixture of two or more substances, forming a single phase
TRUE SOLUTION
2 components
DISPERSED PHASE
DISPERSION MEDIUM
internal phase
DISPERSED PHASE
external phase
DISPERSION MEDIUM
- The diameter of particles is roughly 1 to 500 nm
- Falls between true solution and coarse dispersion
COLLOIDAL SOLUTION
- The diameter of particles is greater than 500 nm
- 2 or more phases
SUPENSION & EMULSIONS
Components/Constituents of true solutions
solute
solvent
lesser amount (solid)
SOLUTE
greater amount (liquid, water)
SOLVENT
solute + solvent
SOLUTION
used to indicate a multi-compartment system in which one or more solute is dissolved in a solvent.
SOLUTION
Drug properties in solution are important because a drug solution is dispersed in
MOLECULAR LEVEL
essential for a drug to exert its chemical, biochemical, and pharmacological effects.
DRUG PROPERTIES
The quantity of a drug that indicates the strength of its chemical and pharmacological activities is not the weight of the drug, but rather the number of molecules or ions available for the drug action.
SOLUTE
used to describe drug’s pharmacologic action
CONCENTRATION / MOLECULAR EXPRESSIONS
Solutes are expressed in
moles, osmoles, meqwt
- A substance (an acid, base, or salt) that is in an aqueous solution ionizes to positive ions (cations) and negative ions (anions)
- Has greater freezing point depression and boiling point elevation than do non-electrolytes of same concentration
ELECTROLYTES
- Substances that do not ionize when dissolve in water and therefore do not conduct electricity through the solution.
- Lesser greater freezing point depression and boiling point elevation
NON-ELECTROLYTES
almost all drugs are
organic compounds
- Substances that completely ionize in water
- Degree of ionization is pH independent
- ionic compounds
STRONG ELECTROLYTES
- Substances that partially ionize in water
- Degree of ionization is pH dependent
- organic compounds w/ EN element
WEAK ELECTROLYTES