Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

STEP 2 AG > MSK/Rheum/Derm > Flashcards

MSK/Rheum/Derm Flashcards

(68 cards)

Start Studying
1
Q

SLE

A

Sx: SEIZURES, autoimmune thrombocytopenia, anemia of chronic dz, CAN HAVE FEVER (no white count)
Dx: ANA (v sensitive) then anti-dsDNA, anti-Smith
Tx: hydroxychloroquine (retinopathy) cyclophosphamide (bladder cancer, MESNA)

***a/w avascular necrosis, mixed cryoglobulinemia, anti-phospholipid syndrome, splenic rupture

In pregnancy: AV block, flare can look like pre-e +MALAR RASH, ARTHRITIS, RBC CASTS, ANA, dec C3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Avascular necrosis

A

Sickle cell, steroids (SLE), infx, alcohol, renal tplant, gradual increasing pain, may not see on XR early, MRI more sens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Supracondylar fx

A

More common in kids, brachial artery/median nerve, compartment syndrome (swelling + intact pulse and neuro)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Systemic sclerosis

A

Diffuse (scl, topoisomerase, ILD, dysphagia smooth muscle atrophy fibrosis) vs cutaneous (CREST, centromere)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Atlantoaxial instability

A

Downs, upper motor signs, incontinence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Ringworm

A

Tinea corporis, topical clotrimazole or terbinafine, if doesn’t work can try PO (azole > griseofulvin side effects), can look worse in immunocomp pts DM HIV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Takayasu arteritis

A

Asian women 10-40 yo, aorta/big vessels, autoimmune, claudication, bruit, bp discrepancy, dx CT/MRI arterial wall thickening, Tx glucocorticoids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Allergic contact dermatitis

A

Vesicular rash exposed surfaces sometimes streaks type 4 hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Ankylosing spondylitis

A

Enthesitis early sign, Dx by XR, HLA-B27 is 90% sensitive but 5% specific cannot use to diagnose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Giant cell tumor

A

Young adult women, soap bubble lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pemphigus vulgaris

A

desmosomes, IgG C3 intercellular deposits, tombstones, FLACCID bullae, Nikosky sign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Complex regional pain syndrome

A

After trauma/surgery, pain out of proportion, looks like an infection but nl inflammatory markers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

When to XR an ankle

A

Point tenderness over malleolus, posterior, can’t bear weight >4 steps

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Clavicle fracture

A

Middle 1/3 usually no surg but nd angiogram

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Carpal tunnel

A

Diabetes!!, severe=loss of strength (sensation doesn’t count) or evidence on nerve imaging studies)–>surgery, otherwise try splint first

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Amyloidosis

A

Can be 2/2 cancer/IBD/infx/arthritis/vasculitis, HEART STUFF, S4 pretty much every organ, dx abd fat pad aspiration bx, tx colchicine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Juvenile idiopathic arthritis

A

Non migratory, slower onset, can bear weight, maybe mild fever SEPTIC CANT BEAR WEIGHT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Osteoarthritis

A

MC, posture-dependent pain (if spine), tx quad strengthening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Rheumatoid arthritis

A

Periarticular erosions, RF, citrillunated protein, DMARDs folate inhibiting (methotrexate check LFTs hepatotoxic), tx ASAP
atlanto-axial, can have pleural exudative effusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Squamous cell vs basal cell

A

SCC: sun-exposed surfaces, central ulceration, immunocomp, scarring, neuro sx (head&neck cervical LN referred otalgia)
BCC: skin-colored, telangiectasias, non-healing, crusting, much more common

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Polymyalgia rheumatica

A

head, neck, shoulders, hip girdle, high ESR/CRP give low dose pred don’t need confirmatory testing, a/w GCA (aortic aneurysm)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Lichen planus

A

Hep C ACEi HCTZ, 5 p’s polygonal papules, plaques, pink/purple, pruritis flexural surfaces tx topical steroids

vag: fucked up red/inflamed ulcers white striae NOT Behcet, bx make sure it’s not cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Psoriatic arthritis

A

DIPs, nails, prednisone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Tophaceous gout

A

Looks like giant nodules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Transient sinovitis
Can bear weight!! Can see b/l effusion on US, preceding viral illness
26
Charcot joint
Denervation leads to altered mechanics and joint deformation
27
Behcet disease
Middle eastern Turkish Asian, ulcers (oral and genital), erythema nodosum, uveitis
28
Polymyositis/Dermatomyositis
Anti-Jo, Anti-Mi-2, prox muscle weakness w/o pain, dermatomyositis +heliotrope rash +Gottrons finger nodules +periorbital edema, dx Ab CK or muscle bx, tx pred, a/w cancer
29
Quadriceps tendon rupture
Low patella (vs patellar tendon rupture patella will be high)
30
Antiphospholipid syndrome
LONG PTT (lab artifact) Anti-cardiolipin, anti-beta2-glycoprotein, CVA/other thrombotic event/preg probs, ACs for lyfe, if SLE add hydroxychloroquine (side effect retinopathy) **pos RPR**
31
Paget dz of bone
HA, may have no sx, Ca Phos nl, inc alk phos, inc urine hydroxyproline LYTIC focal osteoClasts (MM systemic sx, osteomalacia diffuse)
32
Molluscum contagiosum
POXVIRUS flesh colored umbilicated papules, 6-12 mo, worse in HIV
33
SCFE
SURGICAL PINNING
34
Kawasaki disease
tx aspirin & IVIG
35
Myasthenia gravis vs LE
LE +autonomic sx (dry mouth), DECREASED DTRs, gets better w/ repetition, dx by repetitive nerve stimulation MG nicotinic receptors, ptosis, ice pack test/edrophonium, get chest CT for thymoma, tx pyridostigmine, immunosuppresant MYASTHENIC CRISIS acute resp failure tx plex or IVIG
36
Actinic keratosis
white flaky sun-exposed, can do nothing or cryo or fluorouracil topical if really bad, can turn into SCC
37
Secondary gout causes
PV or other myeloprolif disorder, Lesch-Nyhan, xanthine deficiency, CKD, thiazides
38
meniscal tear
Click w/ McMurray, MRI, surg if impairing function or effusion >3w
39
Felty syndrome
Untreated RA --> neutropenia<2,000, frequent sinus infx, splenomegaly
40
Pseudogout
Hemochromatosis/hyperPTH/hypothyroid, Ca crystals rhomboid positively birefringent, usually the knee/monoarticular, trauma/overuse/surgery/illness, chondrocalcinosis
41
Bullous pemphigoid
PD, MS, cancer pts, IgG C3 LINEAR along membrane, tx topical clobetasol
42
Langerhans cell histiocytosis
bones, skin, LAD, HSM, central diabetes insipidus, benign but locally destructive, tx prednisone or curettage
43
Epidermal inclusion cyst
comes and goes, can do nothing or I&D if infected
44
Lyme dz
Months--can get arthritis
45
Serum sickness-like reaction
1-2 w after penicillin, fever urticaria polyarthralgia kind of looks like ARF but in a pt who got tx
46
Age-related sicca syndrome
dry eyes and mouth, dec exocrine fxn, eye drops
47
Psoriasis
sudden onset severe HIV, can be exacerbated by contact irritation
48
Ichthyosis vulgaris
Chronic genetic condition scaling
49
Lumbar strain
NSAIDs, PT if persistent >6w
50
Septic arthritis
vanc for MRSA coverage, gram neg (klebsiella) also common, add CTX if not getting better RA IS A RF
51
Stress fracture
POINT TENDERNESS, skinny pt (shin splint will be diffusely tender, fat pt)
52
Shingles
NSAIDs, >4mo gabapentin or TCA
53
Henoch-Schonlein purpura
Abd pain, IgA, arthralgias, hematuria, INTUSSUSCEPTION
54
Pressure ulcers
Pillows
55
Midshaft humerus fx
Radial nerve
56
Pyoderma gangrenosum
Crohns, UC, granulomatosis w/ polyangiitis
57
Melanoma
``` A - asymmetric B - irregular borders C - colors D - diam>6mm E - evolution ```
58
Brown recluse spider bite
Ulcerated lesion--> eschar +/- debridement
59
Gout tx
Acute indo COLCHICINE if CV risk pt
60
Joint fluid analysis
nl: <200 OA: 200-2K RA: 2-100K Septic: 50-150K
61
How to treat a sunburn
NSAIDs
62
Iliotibial band syndrome
Lateral femoral epicondyle Noble test (pes anserina medial)
63
Erythema multiforme
a/w HSV, mycoplasma (don't get mixed up w/ Lyme, these are a LOT of lesions usually extremities Lyme more truncal)
64
Acne step-up
Topical retinoids --> benzoyl peroxide --> (COMEDONAL salicylic acid) --> topical abx --> PO abx --> (CYSTIC PO istotretinoin)
65
Shoulder dislocation
Posterior=seizure
66
MCL tear
abduction (valgus) laxity NOT MENISCUS (meniscus has clicking Lachman's test)
67
Duchenne muscular dystrophy
GOLD STANDARD DX genetic testing
68
Eczema herpeticum
HSV infx in pt w/ eczema (asthma/atopy on test), new lesions, ND ACYCLOVIR

STEP 2 AG (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions