Multiple Sclerosis Flashcards
(8 cards)
1
Q
what is multiple sclerosis
A
chronic autoimmune disease demyelinating the CNS
2
Q
what is defined as active MS
A
2 relapses in the past 2 years despite treatment with interferon beta
3
Q
what is used to manage relapses
A
methylprednisolone
4
Q
what is used to manage fatigue
A
amantadine
SSRI
modafanil
5
Q
what is used 1st line and 2nd line to manage spasticity (muscle tightness)
A
baclofen
gabapentin
6
Q
what is used 1st and 2nd line to manage oscillopsia (objects appear to vibrate)
A
gabapentin
memantine
7
Q
what is used for emotional lability (rapid mood shifts)
A
amitriptyline
8
Q
what is a precaution for baclofen
A
to increase dose slowly
to avoid major side effects - sedation and hypotonia (decreased muscle tone)
