Multiplechoice

Question 1

Which of the following amino acids has alkaline side chain?
A. Aspartate
B. Lysine
C. Cysteine
D. Tyrosine

Answer 1

B. Lysine

Question 2

Which of the following amino acids has a ring in its structure?
A. Proline
B. Tryptophan
C. Tyrosine
D. Each answer a) – c) is right

Answer 2

D. Each answer a) – c) is right

Question 3

Which of the followings belongs to the group of posttranslation modification of proteins?
A. Poly-A-Tailing
B. Hydroxylation
C. 5´capping
D. Each answer a) – c) is true

Answer 3

B. Hydroxylation

Question 4

Eukaryotic pre-mRNA must go through posttranscriptional modification, that is?
A. 5´capping
B. Poly-A-tailing
C. Splicing
D. Each answer a) – C) is true

Answer 4

D. Each answer a) – C) is true

Question 5

How does the concentration of HCO3
- change, when adding lactic acid to the carbonic
acid/bicarbonate buffer solution?
A. The concentration increases
B. The concentration decreases
C. The concentration increases, or doesn´t change, depending on the amount of lactic
acid added.
D. The concentration does not change

Answer 5

B. The concentration decreases

Question 6

Which of the following amino acids participates in the formation of cross linkages between
tropocollagen fibers?
A. Proline
B. Cysteine
C. Glycine
D. Lysine

Answer 6

D. Lysine

Question 7

What type of bond can be found between complementer bases of the two DNA strands?
A. Disulphide bonds
B. Phosphodiester bonds
C. Van der Waals binding forces
D. Each answer a) – c) is false

Answer 7

D. Each answer a) – c) is false

Question 8

Which of the following lists shows the components of lecithin?
A. Phosphatidic acid + serine
B. Glycerol + 2 fatty acids + phosphate + choline
C. Diacyl-glycerol + phosphate + cholamine
D. Each answer a) – c) is false

Answer 8

B. Glycerol + 2 fatty acids + phosphate + choline

Question 9

Which of the following lists shows the components of cephalin?
A. Phosphatidic acid + serine
B. Glycerol + 2 fatty acids + phosphate + choline
C. Diacyl-glycerol + phosphate + cholamine
D. Each answer a) – c) is false

Answer 9

C. Diacyl-glycerol + phosphate + cholamine

Question 10

What type of curve describes the connection between substrate concentration and enzyme
activity, if the enzyme is not allosterically regulated?
A. Hyperbolic saturation curve
B. Exponential curve
C. Sygmoidal curve
D. Symmetric bell curve

Answer 10

A. Hyperbolic saturation curve

Question 11

Which of the following statements is false from answer a) – c) concerning membrane forming
”cis” unsaturated fatty acids?
A. Increased proportion causes increased membrane rigidity
B. Oleic acid is one of them
C. They may occur in glycerol phosphatids and sphingolipids too
D. Neither of answers a) – c) is false

Answer 11

A. Increased proportion causes increased membrane rigidity

Question 12

It increases enzyme activity:
A. Connection of the positive allosteric effector to the substrate binding site
B. Disconnection of the negative allosteric effector from the allosteric effector binding site
C. Increasing the concentration of the competitive inhibitor
D. Each answer a) – c) is true

Answer 12

B. Disonnection of the negative allosteric effector from the allosteric effector binding site

Question 13

Which of the following statements is true from answer a) – c) concerning facilitated diffusion?
A. Glucose is transported on the basolateral side of the enterocytes by this transport
mechanism
B. Transporter (carrier molecule) is required
C. Energy is not needed
D. Each answer a) – c) is true

Answer 13

D. Each answer a) – c) is true

Question 14

What happens to thr red blood cell if getting in a saline solution of 0.3% concentration?
A. Red blood cell disintegrate(membrane disruption, hemolysis).
B. Red blood cells shrink (plasmolysis)
C. The fate of red blood cells depends mainly on the pH of the milieu.
D. There is no change observed

Answer 14

A. Red blood cell disintegrate(membrane disruption, hemolysis).

Question 15

Which of the following proteins has quarternary structure?
A. Collagen
B. Lactate dehydrogenase
C. Β-keratin
D. None of the proteins a) – c) has quarternary structure

Answer 15

B. Lactate dehydrogenase

Question 16

Which of the following proteins belong(s) to the group of storage proteins?
A. Succinate dehydrogenase
B. Actin
C. Casein
D. Each answer a) – c) is correct

Answer 16

C. Casein

Question 17

Which property of the enzyme is determind by the catalytic center?
A. Reaction specificity
B. Substrate specificity
C. The optimal temperature for the operation of enzyme
D. Each answer a) – c) if false

Answer 17

A. Reaction specificity

Question 18

Which of the following statements is false from answer a) – c) concerning allosteric enzyme
inhibition?
A. The inhibitor attaches to the allosteric effector binding site
B. The structure of the substrate and inhibitor is typically similar
C. Concentration changes of the substrate do not influence the degree of inhibition
D. Each answer a) – c) is false

Answer 18

B. The structure of the substrate and inhibitor is typically similar

Question 19

Which of the following enzymes belongs to the enzyme class oxidoreductases?
A. Phosphoglucomutase
B. DNA ligase
C. Amylase
D. Each answer a) – c) is false

Answer 19

D. Each answer a) – c) is false

Question 20

Which of the following molecules is built up from thymine + deoxy-ribose + 2phosphate groups?
A. Deoxy-thymidine
B. dTDP
C. dTTP
D. Each answer a) – c) is false

Answer 20

B. dTDP

Question 21

The transcription of what type of RNA is done by DNA polymerase I in eukaryotes?
A. mRNA and snRNA
B. tRNA and rRNA
C. rRNA
D. Each answer a) – c) is false

Answer 21

C. rRNA

Question 22

Why is the process of DNA replication semiconcervative?
A. The duplicated genetic substance contains only newly formed DNA
B. One DNA molecule of the duplicated genetic substance contains only original, the other
DNA contains only new strands, produced in the process of replication
C. Both DNA molecules of the duplicated genetic substance have one original and one new strand, produced in the process of replication
D. Each answer a) – c) is false

Answer 22

C. Both DNA molecules of the duplicated genetic substance have one original and one new strand, produced in the process of replication

Question 23

Which of statements a) – c) is false concerning replication?
A. The main repair enzyme is DNA polymerase B in eukaryotes
B. Elongation of the chain happens by the DNA polymerase I in prokaryotes
C. Elongation on the leading strand of DNA happens in the direction of 5´-> 3
D. None of statements a) – c) is false

Answer 23

B. Elongation of the chain happens by the DNA polymerase I in prokaryotes

Question 24

Which of the answers a) – c) is true for a transformed host cell containing recombinant plasmid, if
the cleavage site of the used restriction endonuclease is in the ampicillin resistance gene?
A. The cell can not be cultured on a medium containing ampicillin
B. The cell can be cultured on a medium containing ampicillin too
C. The cell can be cultured on a medium containing ampicillin only
D. Each answer a) – c) is false

Answer 24

A. The cell can not be cultured on a medium containing ampicillin

Question 25

``` The oxidation of which of the following molecules covers the majority of the energy needs of liver? A. Glucose B. Fatty acids C. Amino acids D. Each answer a) – c) is false ```

Answer 25

B. Fatty acids

Question 26

``` Which of the following cells is/are able to produce hyaluronidase? A. Sperms B. Muscle cells C. Nerve cells D. Each answer a) – b) is false ```

Answer 26

A. Sperms

Question 27

If during the operation of Na-K-pump 2 ATP molecules are hydrolysed, how many K+ ions can be pumped in the cell by using up this released energy? A. 2 B. 4 C. 6 D. Each answer a) – c) is false

Answer 27

B. 4

Question 28

``` Which of the followings is necessary for the initiation of transcription in prokaryotes? A. DNA-dependent B. Sigma factor C. DNA template D. Each molecule a) – c) is necessary ```

Answer 28

D. Each molecule a) – c) is necessary

Question 29

What is code? A. The triple units of bases (nucleotides) found on the sense (coding) strand of DNA B. The triple units of bases (nucleotides) found on the mRNA C. The triple units of amino acids of protein produced from mRNA D. The short segment of one of the loop of tRNA

Answer 29

A. The triple units of bases (nucleotides) found on the sense (coding) strand of DNA

Question 30

What is non-sense mutation? A. The frame shift B. That type of mutations, where the change of nucleotide results the change of amino acids C. That type of mutations, where the new triplet formed does not encode amino acid D. Each answer a) – c) if false

Answer 30

C. That type of mutations, where the new triplet formed does not encode amino acid

Question 31

What is ,,5`capping? A. Excision of introns during the maturation of mRNA B. 7-methyl-guanosine cap is attached to the 5´end of mRNA C. Poly-A-tailing on the 3´end of mRNA D. Each answer a) – c) is false

Answer 31

B. 7-methyl-guanosine cap is attached to the 5´end of mRNA

Question 32

``` Which of the following intermediary product is formed during the activation of amino acids? A. Aminoacyl-mRNA B. tRNA – AMP C. Aminoacyl-AMP D. Each answer a) – c) is false ```

Answer 32

C. Aminoacyl-AMP

Question 33

What is the function of the P binding site of the ribosomal large subunit in eukaryotes? A. Binding of methionyl-tRNA, later of peptidyl-tRNA B. Binding of tRNA transporting the new, be built in amino acid C. This is the binding site of RNA polymerase II D. Each answer a) – b) is false

Answer 33

A. Binding of methionyl-tRNA, later of peptidyl-tRNA

Question 34

What is the function of the DHU loop of tRNA? A. Binding of aminoacyl-tRNA synthetase B. Binding to the ribosomal large subunits C. Binding of amino acids to the CCA sequence of the 3´end of tRNA D. Each answer a) – c) is false

Answer 34

A. Binding of aminoacyl-tRNA synthetase

Question 35

Which of the following processes is catalyzed by translocase during the elongation of translation A. Translocation of peptidyl-tRNA from A to P binding site B. Translocation of the peptide chain being elongated onto the aminoacyl-tRNA on the A binding site and formation of peptide bonds C. Binding of the new aminoacyl-tRNA to the A bindingsite D. Each answer a) – c) is false

Answer 35

A. Translocation of peptidyl-tRNA from A to P binding site

Question 36

``` Which of the following is necessary for the DNA polymerase III? A. Okasaki-fragments B. Ribonucleoside triphosphate (NTP-s) C. Template DNA-strand D. Each answer a) – c) is true ```

Answer 36

D. Each answer a) – c) is true

Question 37

``` Which of the following is necessary for the operation of cytochrome P450 enzymes? A. NAD+ B. NADP+ C. Biotin D. Each cofactor a) – c) is needed ```

Answer 37

B. NADP+

Question 38

``` Which of the followings is necessary for reverse transcription? A. Restriction endonuclease B. Olygo-T primer C. DNA dependent DNA polymerase D. Each answer a) – c) is true ```

Answer 38

B. Olygo-T primer

Question 39

``` Which of the following fatty acids belongs to the class omega 3? A. Oleic acid B. Linoleic acid C. Linolenic acid D. Each answer a) – c) is false ```

Answer 39

C. Linolenic acid

Question 40

``` Which is a ketose? A. Glucose B. Fructose C. Galactose D. Each answer a) – c) is true ```

Answer 40

B. Fructose

Question 41

``` In which part of the cells are enzymes of respiratory chain found? A. Mitochondria B. Nucleus C. Cytoplasm D. Ribosome ```

Answer 41

A. Mitochondria

Question 42

``` Which of the following amino acids contains the most nitrogens? A. Methionine B. Arginine C. Glutamine D. All the same ```

Answer 42

B. Arginine

Question 43

``` Which of the following are co-factors? A. NADP B. NAD C. PALP D. All of them ```

Answer 43

D. All of them

Question 44

``` How much will the intracellular weight be if a dog is 12 kg? A. 1 kg B. 3 kg C. 4 kg D. 8 kg ```

Answer 44

D. 8 kg

Question 45

``` Which one of these has oxygen attached in the side group? A. Asparagine B. Glutamate C. Tyrosine D. All ```

Answer 45

D. All

Question 46

``` Which one of these uses facilitated diffusion? A. Glucose B. Urea C. Oleic acid D. None of them ```

Answer 46

A. Glucose

Question 47

``` Which muscle is continuous acting? A. White – fast twich fiber(short lasting) B. Red – slow twich (continuous) C. Transition D. All of them ```

Answer 47

B. Red – slow twich (continuous)

Question 48

``` Which one is an omega 3? A. Oleic acid B. Linoleic acid C. Linolenic acid D. Arachidonic acid E. None of them ```

Answer 48

C. Linolenic acid

Question 49

Which one has a restriction endonuclease? A. Bacteria B. Virus C. Bacteria phage D. Each answer a) – c) none of them above

Answer 49

A. Bacteria

Question 50

``` What do you need to finish a protein? A. GTP B. ATP C. snRNA D. Neither of them ```

Answer 50

A. GTP

Question 51

``` Which one of these needs energy? A. Binding of peptide tRNA to P site B. Peptidyl translocase enzyme C. Removal of tRNA from ribosome D. All of them ```

Answer 51

D. All of them