Flashcards in Muscle Relaxants Deck (43)
Intubating dose of Vecuronium?
Intubating dose of Pancuronium?
Non-depolarizing NMB with the longest duration of action?
Non-depolarizing NMB with the most vagolytic side effect?
When should you avoid succ in children?
Men younger than 5 years (undiagnosed Duchenne muscular dystrophy)
Difference in cardiac side effects seen with succinylcholine in adults vs. children?
Children: sympathotonic so they will brady after succ
Adults: vagotonic so they will become tachy
What is the best clinical indicator of adequate muscle function after NMB use?
Sustained head lift (at least 70% function has returned)
What T4/T1 ratio ensure the patient can maintain adequate ventilation?
What is the gold standard of monitoring NMB?
How is the duration of action of esmolol affected by a patient with a dibucaine number of 20%?
Not affected at all. Esmolol is metabolized by esterases in the RBCs (different from pseudocholinesterase that breaks down succinylcholine in this homozygous)
How are NMB's affected by Lambert-Eaton Syndrome?
Increased sensitivity to depolarizing and non-depolarizing NMBs (decreased ACh at the junction -> increased sensitivity to non-depolarizing -> increased extra-junctional receptors -> increased sensitivity to depolarizing)
Does cerebral palsy increase the risk of hyperkalemia with succinylcholine use?
No since there is no increase in the extra-junctional receptors