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Flashcards in Muscle Relaxants Deck (43)
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31

Intubating dose of Vecuronium?

0.1 mg/kg

32

Intubating dose of Pancuronium?

0.1 mg/kg

33

Non-depolarizing NMB with the longest duration of action?

Pancuronium

34

Non-depolarizing NMB with the most vagolytic side effect?

Pancuronium

35

When should you avoid succ in children?

Men younger than 5 years (undiagnosed Duchenne muscular dystrophy)

36

Difference in cardiac side effects seen with succinylcholine in adults vs. children?

Children: sympathotonic so they will brady after succ
Adults: vagotonic so they will become tachy

37

What is the best clinical indicator of adequate muscle function after NMB use?

Sustained head lift (at least 70% function has returned)

38

What T4/T1 ratio ensure the patient can maintain adequate ventilation?

0.9

39

What is the gold standard of monitoring NMB?

Mechanomyography

40

How is the duration of action of esmolol affected by a patient with a dibucaine number of 20%?

Not affected at all. Esmolol is metabolized by esterases in the RBCs (different from pseudocholinesterase that breaks down succinylcholine in this homozygous)

41

How are NMB's affected by Lambert-Eaton Syndrome?

Increased sensitivity to depolarizing and non-depolarizing NMBs (decreased ACh at the junction -> increased sensitivity to non-depolarizing -> increased extra-junctional receptors -> increased sensitivity to depolarizing)

42

Does cerebral palsy increase the risk of hyperkalemia with succinylcholine use?

No since there is no increase in the extra-junctional receptors

43

How do you calculate the RSBI (rapid shallow breathing index)? What is a good value for extubation?

RSBI = RR / TV (in liters)
RSBI