Flashcards in Mycobacterium Tuberculosis Deck (64):
Also known as Koch bacilli, AFB or Tubercle bacilli, Captain of all men of death.
AFB and gram + bacilli aerobic, NM, NS, NE; requires enriched media and 5-10% of CO2.
Slow grower with a generation time of 20 hours; multiply by fermentation; contains much granules; requires whole egg for growth; produces cauliflower like growth on culture medium, luxuriant growth (eugonic); causes tuberculosis in man; long, slender, granular curved or rounded end.
Medium used in mycobacterium tuberculosis.
Lowenstein, petroffs, Dorset's, corpers
Pathogenecity of mycobacterium tuberculosis
No toxins produced
Spinal disease of TB
Skin disease of TB
Cervical lymph nodes disease of TB
Also know as leprae bacilli, hansens bacilli
exhibits cigar packet arrangement
Non culturable on artificial medium but can be maintained in the footpads of armadillo
Anesthetic type; non-progressive and benign with few organism on skin lesions; + leprominb test
Paucibacillary (Tuberculoid Leprosy)
Nodular type; course is progressive and malign with numerous organisms on skin lesions: - lepromin test
Multi bacillary (Lepromatous leprosy)
Differentiating point of M.gordonae from M.scrofulaceum
Differentiates M.fortuitum-Chelonei + from M.phlei -
Iron Uptake test
Differentiates M.flavescens + from M.szulgai -
NaCl tolerance test
Causes TB in cows; source of Bacille Calmette Guerin
Pigment colonies presence of light
Pigments colonies in the presence of darkness/light
Non-Photochromogens and Rapid Growers; - to niacin and nitrate, + tween 80 and heat stable catalase
Non-photochromogens and Rapid Growers; requires Hemin for growth.
Non-photochromogens and Rapid Growers; battery bacillus; all tests are - except for the heat stable catalase and pyrazinamidase test
Non-photochromogens and Rapid Growers; may be isolated from gastric lavage
The rapid growers;
+ pink to red color
Strongly + to Arysulfatease test
+ to Arysulfatease test
Negative or weakly + Arysulfatease test
M.phlei and M.smegmatis
The slow growers. Positive
Gm+ bacilli, NM, NE, alpha hemolytic on BAP. Catalase, INDOLE, oxidase and nitrate negative; ferments glucose and lactose. May cause erysipeloid. H2s positive, produce h2s in the butt of TSI media; is better know as veterinary pathogen than as a human pathogen.
Colonies of Erysipelothrix rhusiopathiae were described as
Lampbrush or test tube brush.
When cultured on blood agar or some other nutrient medium Erysipelothrix rhusiopathiae forms.
Notably large colonies.
Treatment of Erysipelothrix rhusiopathiae usually consist of
Penicillin G, ampicillin or cephalonthin
Most clinical strains of Erysipelothrix rhusiopathiae have been found to be resistant
Small grm + coccobacilli, NAF, shows tumbling motility; Can grow on 25-35,40 and 42C; catalase and vp test +; indole, oxidase and urease test negative; ferments glucose, maltose; bile Esculin hydrolysis +
Listeria monocytogenes on BAP
Produce a narrow band band of beta hemolysis
On agar surface the Erysipelothrix rhusiopathiae
Produce umbrella like growth "Inverted Chrismtas tree pattern
Erysipelothrix rhusiopathiae can cause
Listeriosis, Meningitis, Meningoencephalitis and perinatal septicemia.
Two species of human pathogenic significance in listeria monocytogenes
Listeria monocytogenes and listeria Ivanovo
Susceptibility test for Listeria Monocytogenes. Suspension into rabbit eye or guinea pig. + result purulent conjunctivitis develops after 24 hours.
Commonly known as probiotic or good bacteria. Normal flora of the mouth, GIT and vaginal canal. Rare cause of bacteremia and pneumonia; produce large qnty of lactic acid. Gm+, catalase -, pleomorphic, NM, H2S -, does not hydrolyze Esculin
If one fermenter is produced
Numerous fermentation and there are products other than lactic acid
Common name of Lactobacillus acidophilus
Products like yoghurt
For yakult milk
L.delbruecki subsp. bulgaricus
Can also be found in the intestine
Facultative anaerobe and multiplied by transverse fission; all are M producing axial fibrils, a long flagellum like intracellular organelle that are responsible for its motility. Unicellular organisms with flexus structure. Dark field microscopy
Causative agent of syphillis
Disease of blood vessel and peri vascular areas
Commonly observed during the early stages when treated with penicillin
Closely resembles tawa
Disease of bones and skin, non verenal, transmitted thru aids of of flies; causative agent of yaws
Infection if the feet which cause a crippling form of disease
Affects only the skin and becomes de pigmented; causative agent of carate or punta which is characterized by hyperpigmented lesion.
Thin, flexible organisms with tightly coiled spirals and one or both ends mag be bent to form a hook. Strict aerobic, oxidase and catalase +, peroxidase +; causative agent of Weil's disease
Other names of leptosira
Swineherd's disease, Fort Bragg Fever, Pretibial Fever, canicola fever and autumnal fever
2 recognized fever of leptosira
Leptosira interrogans and leptosira biflexa
Disease produced is relapsing fever, tick fever, borreliosis or famine fever. Loosely coiled, irregular in shape, highly flexible spiral organisms, motile, microaerophilic. Can be visualized by staining with aniline dyes.
Louseborbe or epidemic relapsing fever which is transmitted to man by the human body louse.
Tick borne or endemic relapsing fever which is transmitted to man by ticks:Ornithodoros species.
Borrelia turicatae and Borrelia parkeri