Mycobacterium Tuberculosis Flashcards

(64 cards)

0
Q

AFB and gram + bacilli aerobic, NM, NS, NE; requires enriched media and 5-10% of CO2.

A

Mycobacterium tuberculosis

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1
Q

Also known as Koch bacilli, AFB or Tubercle bacilli, Captain of all men of death.

A

Mycobacterium tuberculosis

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2
Q

Slow grower with a generation time of 20 hours; multiply by fermentation; contains much granules; requires whole egg for growth; produces cauliflower like growth on culture medium, luxuriant growth (eugonic); causes tuberculosis in man; long, slender, granular curved or rounded end.

A

Mycobacterium tuberculosis

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3
Q

Medium used in mycobacterium tuberculosis.

A

Lowenstein, petroffs, Dorset’s, corpers

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4
Q

Pathogenecity of mycobacterium tuberculosis

A

No toxins produced

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5
Q

Spinal disease of TB

A

Pott’s disease

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6
Q

Skin disease of TB

A

Lupus Vulgaris

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7
Q

Cervical lymph nodes disease of TB

A

Scrotula

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8
Q

Also know as leprae bacilli, hansens bacilli

A

M.Leprae

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9
Q

exhibits cigar packet arrangement
Non culturable on artificial medium but can be maintained in the footpads of armadillo
Causes leprosy

A

M.leprae

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10
Q

Anesthetic type; non-progressive and benign with few organism on skin lesions; + leprominb test

A

Paucibacillary (Tuberculoid Leprosy)

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11
Q

Nodular type; course is progressive and malign with numerous organisms on skin lesions: - lepromin test

A

Multi bacillary (Lepromatous leprosy)

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12
Q

Differentiating point of M.gordonae from M.scrofulaceum

A

Tween 80
+ M.gordonae
- M.scrofulaceum

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13
Q

Differentiates M.fortuitum-Chelonei + from M.phlei -

A

Arylsulfatase test

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14
Q

M.fortuitum +

A

Iron Uptake test

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15
Q

Differentiates M.flavescens + from M.szulgai -

A

NaCl tolerance test

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16
Q

Causes TB in cows; source of Bacille Calmette Guerin

A

M.bovis

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17
Q

Pigment colonies presence of light

A

Photochromogens

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18
Q

Photochromogens

A

M.szulgai

M.kansasii/M.simiae/M.marinum

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19
Q

Pigments colonies in the presence of darkness/light

A

Scotochromogens

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20
Q

Schotochromogens

A

M.scrofulaceum
M.szulgai
M.gordonae
M.xenopi

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21
Q

Non-Photochromogens and Rapid Growers; - to niacin and nitrate, + tween 80 and heat stable catalase

A

M.malmoense

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22
Q

Non-photochromogens and Rapid Growers; requires Hemin for growth.

A

M.haemophilum

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23
Q

Non-photochromogens and Rapid Growers; battery bacillus; all tests are - except for the heat stable catalase and pyrazinamidase test

A

M.avium-intracellulare

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24
Non-photochromogens and Rapid Growers; may be isolated from gastric lavage
M.gastri
25
The rapid growers; | + pink to red color
Arysulfatease test
26
Strongly + to Arysulfatease test
M.fortuitum
27
+ to Arysulfatease test
M.chelonei
28
Negative or weakly + Arysulfatease test
M.phlei and M.smegmatis
29
The slow growers. Positive
Niacin test
30
Gm+ bacilli, NM, NE, alpha hemolytic on BAP. Catalase, INDOLE, oxidase and nitrate negative; ferments glucose and lactose. May cause erysipeloid. H2s positive, produce h2s in the butt of TSI media; is better know as veterinary pathogen than as a human pathogen.
Erysipelothrix rhusiopathiae
31
Colonies of Erysipelothrix rhusiopathiae were described as
Lampbrush or test tube brush.
32
When cultured on blood agar or some other nutrient medium Erysipelothrix rhusiopathiae forms.
Notably large colonies.
33
Treatment of Erysipelothrix rhusiopathiae usually consist of
Penicillin G, ampicillin or cephalonthin
34
Most clinical strains of Erysipelothrix rhusiopathiae have been found to be resistant
Super-antibiotic vancomycin
35
Small grm + coccobacilli, NAF, shows tumbling motility; Can grow on 25-35,40 and 42C; catalase and vp test +; indole, oxidase and urease test negative; ferments glucose, maltose; bile Esculin hydrolysis +
Listeria Monocytogenes
36
Listeria monocytogenes on BAP
Produce a narrow band band of beta hemolysis
37
On agar surface the Erysipelothrix rhusiopathiae
Produce umbrella like growth "Inverted Chrismtas tree pattern
38
Erysipelothrix rhusiopathiae can cause
Listeriosis, Meningitis, Meningoencephalitis and perinatal septicemia.
39
Two species of human pathogenic significance in listeria monocytogenes
Listeria monocytogenes and listeria Ivanovo
40
Susceptibility test for Listeria Monocytogenes. Suspension into rabbit eye or guinea pig. + result purulent conjunctivitis develops after 24 hours.
Anton's test
41
Commonly known as probiotic or good bacteria. Normal flora of the mouth, GIT and vaginal canal. Rare cause of bacteremia and pneumonia; produce large qnty of lactic acid. Gm+, catalase -, pleomorphic, NM, H2S -, does not hydrolyze Esculin
Lactobacillus acidophilus
42
If one fermenter is produced
Homofermenter
43
Numerous fermentation and there are products other than lactic acid
Heterofermenter
44
Common name of Lactobacillus acidophilus
Doderlein bacillus
45
Products like yoghurt
L.bulgaricus
46
For yakult milk
Lactobacillus-shirota strain
47
Swiss cheese
L.delbruecki subsp. bulgaricus
48
Can also be found in the intestine
L.cassei
49
Facultative anaerobe and multiplied by transverse fission; all are M producing axial fibrils, a long flagellum like intracellular organelle that are responsible for its motility. Unicellular organisms with flexus structure. Dark field microscopy
Spirochetes
50
Causative agent of syphillis
T.pallidum
51
Disease of blood vessel and peri vascular areas
Syphillis
52
Commonly observed during the early stages when treated with penicillin
Jarisch-Herxheimer Reaction
53
Closely resembles tawa
Bejel
54
Disease of bones and skin, non verenal, transmitted thru aids of of flies; causative agent of yaws
T.pertenue
55
Infection if the feet which cause a crippling form of disease
Crab yaws
56
Affects only the skin and becomes de pigmented; causative agent of carate or punta which is characterized by hyperpigmented lesion.
T.carateum
57
Thin, flexible organisms with tightly coiled spirals and one or both ends mag be bent to form a hook. Strict aerobic, oxidase and catalase +, peroxidase +; causative agent of Weil's disease
Leptospira
58
Other names of leptosira
Swineherd's disease, Fort Bragg Fever, Pretibial Fever, canicola fever and autumnal fever
59
2 recognized fever of leptosira
Leptosira interrogans and leptosira biflexa
60
Disease produced is relapsing fever, tick fever, borreliosis or famine fever. Loosely coiled, irregular in shape, highly flexible spiral organisms, motile, microaerophilic. Can be visualized by staining with aniline dyes.
Borria
61
Louseborbe or epidemic relapsing fever which is transmitted to man by the human body louse.
Borrelia recurrentis
62
Tick borne or endemic relapsing fever which is transmitted to man by ticks:Ornithodoros species.
Borrelia turicatae and Borrelia parkeri
63
Causative agent of avian spircohetosis
Borrelia anserina