Neoplasia 1

Question 1

A swelling of any sort but modern usage equates this term with a neoplastic mass.

Answer 1

Tumor

Question 2

An abnormal mass the growth of which is purposeless, autonomous

Answer 2

Neoplasm (from Greek “new growth”)

Question 3

The study of neoplasms

Answer 3

Oncology (from Greek “mass or tumor”)

Question 4

Synonymous with malignant neoplasm

Answer 4

Cancer

Question 5

Not life threatening

Answer 5

Benign

Question 6

Malignant epithelial neoplasm

Answer 6

CARCINOMA

Question 7

benign Surface epithelium (non-glandular) neoplasm

Answer 7

papilloma

Question 8

malignant Surface epithelium (non-glandular) neoplasm

Answer 8

carcinoma (squamous, basal cell, epidermoid)

Question 9

benign Glandular neoplasm

Answer 9

adenoma

Question 10

malignant Glandular neoplasm

Answer 10

adenocarcinoma

Question 11

malignant Connective Tissue neoplasm

Answer 11

sarcoma

Question 12

benign Fibrous neoplasm

Answer 12

fibroma

Question 13

malignant Fibrous neoplasm

Answer 13

fibrosarcoma

Question 14

benign Cartilage neoplasm

Answer 14

chondroma

Question 15

malignant Cartilage neoplasm

Answer 15

chondrosarcoma

Question 16

benign Bone neoplasm

Answer 16

osteoma

Question 17

malignant Bone neoplasm

Answer 17

osteosarcoma

Question 18

benign Fat neoplasm

Answer 18

lipoma

Question 19

malignant Fat neoplasm

Answer 19

liposarcoma

Question 20

malignant Liver neoplasm

Answer 20

hepatoma

Question 21

malignant skin neoplasm

Answer 21

melanoma

Question 22

malignant Lymphatics neoplasm

Answer 22

lymphoma

Question 23

benign Uterine Smooth Muscle Tumors

Answer 23

leiomyoma

Question 24

malignant Uterine Smooth Muscle Tumors

Answer 24

leiomyosarcoma

Question 25

Tumors arising from totipotential germ cells which have the capacity to differentiate along the three germ layers: Endoderm (e.g., gut epithelium) Ectoderm (e.g. skin) Mesoderm (e.g. fat)

Answer 25

teratoma

Question 26

Prototype of the totipotential cell is the

Answer 26

zygote which gives rise to the fetus

Question 27

Characteristics of malignant tumors

Answer 27

severe atypia and pleomorphism, many mitosis, increased nucleus to cytoplasm ratio, prominent nucleolus, usually abnormal ploidy

Question 28

Level of differentiation of the tumor cells and, in some cancers, the number of mitoses or architectural features

Answer 28

grade

Question 29

extent of spread of a cancer within the patient

Answer 29

stage

Question 30

Abnormal transformation of a fully differentiated adult tissue of one kind into a differentiated tissue of another kind.

Answer 30

Metaplasia

Question 31

Loss of structural differentiation, correlates with tumor aggressiveness.

Answer 31

Anaplasia

Question 32

Disorderly, but non-neoplastic, proliferation

Answer 32

Dysplasia

Question 33

a modern term that encompasses dysplastic and carcinoma in situ lesions whose component cells do not violate the basement membrane

Answer 33

Intraepithelial neoplasia

Question 34

Tumor greater than _____ requires blood vessel support. _____ as a major player.

Answer 34

1-2mm3 Vascular endothelial growth factor (VEGF) Supports tumor growth and metastasis