Neoplasia VIII Flashcards

1
Q

What type of cancer is caused by Carbon tetrachloride?

A

Centrilobular necrosis, fatty change (p.223)

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2
Q

What type of cancer is caused by nitrosamines (smoked foods)?

A

Gastric cancer (p.223)

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3
Q

What types of cancer are caused by cigarette smoke?

A

Squamous cell carcinoma, squamous cell and small cell carcinoma, renal cell carcinoma, transitional cell carcinoma, pancreatic adenocarcinoma (p.223)

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4
Q

What type of cancer is caused by asbestos?

A

Bronchogenic carcinoma > mesothelioma (p.223)

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5
Q

What types of cancer are caused by arsenic?

A

Squamous cell carcinoma, angiosarcoma (p.223)

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6
Q

What type of cancer is caused by Naphthalene (aniline) dyes?

A

Transitional cell carcinoma (p.223)

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7
Q

What type of cancer is caused by alkylating agents?

A

Leukemia (p.223)

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8
Q

What paraneoplastic syndrome is caused by elevated ACTH or ACTH-like peptide?

A

Cushing’s syndrome (p.223)

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9
Q

What paraneoplastic syndrome is caused by ADH?

A

SIADH (p.223)

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10
Q

What condition is caused by excess PTHrP that ultimately causes a paraneoplastic syndrome?

A

Hypercalcemia (p.223)

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11
Q

What condition is caused by excess 1,25-(OH)2D3 (calcitriol) that ultimately causes a paraneoplastic syndrome?

A

Hypercalcemia (p.223)

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12
Q

What paraneoplastic syndrome is caused by elevated Erythropoietin?

A

Polycythemia (p.223)

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13
Q

What paraneoplastic syndrome is caused by Antibodies against presynaptic Ca2+ channels at the NMJ?

A

Lambert-Eaton syndrome (muscle weakness) (p.223)

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14
Q

What neoplasm is associated with Cushing’s syndrome?

A

Small cell lung carcinoma (p.223)

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15
Q

What neoplasms is associated with SIADH?

A

Small cell lung carcinoma and intracranial neoplasms (p.223)

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16
Q

What neoplasms are associated with Hypercalcemia caused by elevated PRHrP or 1,25-(OH)2D3?

A

Squamous cell lung carcinoma, renal cell carcinoma, breast cancer, Hodgkin’s lymphoma, some non-Hodgkin’s lymphomas (p.223)

17
Q

What neoplasms are associated with Polycythemia?

A

Renal cell carcinoma, hemangioblatoma, hepatocellular carcinoma, pheochromocytoma (p.223)

18
Q

What neoplasm is associated with Lambert-Eaton syndrome?

A

Small cell lung carcinoma (p.223)

19
Q

What hormone/agent is elevated in Cushing’s syndrome?

A

ACTH or ACTH-like peptide (p.223)

20
Q

What hormone/agent is elevated in SIADH?

A

ADH (p.223)

21
Q

What hormones/agents are elevated in Hypercalcemia?

A

PTHrP or 1,25-(OH)2D3 (calcitrol) (p.223)

22
Q

What hormone/agent is elevated in Polycythemia?

A

Erythropoietin (p.223)

23
Q

What agent is elevated in Lambert-Eaton syndrome?

A

Antibodies against presynaptic Ca2+ channels at the NMJ (p.223)

24
Q

What are psammoma bodies?

A

Laminated, concentric, calcific spherules (p.223)