Neuro Flashcards

(49 cards)

1
Q

Microglial Cells

A
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2
Q

Astrocytes

A

glial cells in CNS

maintain the BBB and provide support to neurons

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3
Q

Ependymal Cells

A
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4
Q

Oligodendrocytes

A

form the myelin sheath in CNS

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5
Q

Satellite cells

A

PNS

cling to neurons, synaptic endings and capillaries

provide support and nutrients to the cell bodies of neurons

**NO regeneration – this is shwann

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6
Q

Schwann Cells

A

PNS

surround all peripheral nerve fibers and form meylin sheaths in thicker nerve fibers

VITAL to regeneration of damaged peripheral nerve fibers

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7
Q

neuron cell body

A

Nuclei : clusters of neuron cell bodies in CNS

Ganglia: clusders of neuron cell bodies in PNS

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8
Q

Neuron processes

A

Tract: bundle of neuron processes in CNS

Nerves: bundles of neuron processes in PNS

two types of processes:
1. dendrites
2. Axon

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9
Q

Resting state

A

all Na+ and K+ channels are closed

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10
Q

activation gates

A

open with depolarization… this allows Na+ to enter cell

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11
Q

inactivation gates

A

open at rest, blocks channel once it is open to prevent more Na+ from entering cell

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12
Q

Depolarization

A

Na+ channels open
- depolarizing local currents open the voltage gated Na+ channels…. and Na+ RUSHES INTO CELL

Na+ activation & inaction gates open

Na+ influx causes more depolarization which opens more Na+ channels

@threshold… -55 to -50 V, positive feedback causes opening of all Na+ channels
- this causes a large action potential spoke
- membrane polarity jumps to +3V

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13
Q

Repolarization

A

Na+ channels are inactivating and K+ channels open

Na+ channel inactivation gates close…

voltage gated K+ channels open

REPOLARIZATION: when membrane returns to resting membrane potential

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14
Q

Hyperpolarization

A

some K+ channels remain open and Na+ channels reset

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15
Q

Ca2+ entry causes synaptic vesicles to release neurotransmitter

A

Ca2+ causes synaptotagmin protein to react with SNARE proteins …. which control fusion of synaptic vesicles with axon membrane

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16
Q

sympathetic chain ganglia

A

collection of nerve fiber cell bodies in the Sympathetic chain

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17
Q

Visceral motor neurons located in the intermediolateral horn of the spinal cord from…

A

T1-L2

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18
Q

axons can take three different paths

A

can exit at different levels of the nerves

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19
Q

Splanchnic nerve

A

Sympathetic nerve…

coming AWAY from the sympathetic chain…

outside

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20
Q

Preganglionic nerves… SYMPATHETIC and PARASYMPATHETIC release….?

A

release Acetylcholine

21
Q

Sweat glands, and certain blood vessels release…

A

Acetylcholine…

22
Q

POST-ganglionic sympathetic nerves release…

A

Norepinephrine (NE)

23
Q

which amino acid leads to the synthesis of Ne and EPI

24
Q

tyrosine to NE pathway

A

Tyrosine… DOPA… Dopamine… Norepinephrine

25
alpha
located on blood vessels -- vasoconstriction
26
beta-1
beta constrictors force of muscle contraction activation -- increases HR and contractility
27
Beta-2
cause vasodilation anything that gets upregulated activation -- bronchial dialtion, dialtion of blood vessels in skeletal muscle and glycogenolysis
28
Occulomotor Nerve
Fibers to pupillary pshincters and ciliary muscle
29
Facial Nerve
CN 7 fibers to nasal, lacrimal and submandibular gland
30
Glossopharyngeal nerve
CN 9 fibers to parotid gland
31
vagus N
CN 10 motor inputs to visceral organs
32
sacral segments
fibers to descending colon rectum bladder and genitalia
33
Parasympathetic Functions
nerves release Acetylcholine (ACh) at nerve endings these are CHOLINERGIC nerves ALL preganglionic sympathetic nerves release acetylcholine.... ALL postganglionic sympathetic nerves release ACh...
34
ACh stimulates... what?
ACh stimulates nicotinic and muscarinic receptors
35
Nicotinic receptors
located in synapses between pre and post ganglionic neurons and at the NEUROMUSCULAR JUNCTION part of the sympathetic nervous system voluntary muscle coordinator BETWEEN pre and post neurons for sympathetic and parasympathetic
36
muscarinic receptors
Located at ALL effectors cell stimulated by post ganglionic parasympathetic fibers only at effector organs
37
adrenergic receptors
heart -- beta 1 lung -- beta 2 stomach -- alpha
38
sweat gland receptors
acetylcholine
39
Structures of the brain
40
Ascending tract
41
Descending Tract
42
Brainstem questions....
are most often the medulla!
43
Brain Stem parts & function
44
Endoderm
glands, other organs,
45
Mesoderm
muscles, bones, connective tissues
46
Ectoderm
three parts: 1. Neural crest 2. Neuroectoderm (brain and spinal cord) 3. Surface Ectoderm menstrual cycle & vision... pituitary -- FSH, LH, pituitary adenoma... crosses the optic chiasm
47
Anterior pituitary
balances menstrual cycle
48
Middle Cranial Fossa
49
ischemia
generalized decreased blood flow shock, cardiac arrest, hypoxic episodes ** the purkinje cells of the cerebellum and pyramidal neurons of sommer's sector in the hippocampus -- sensitive to ischemic damage and are likely to demonstrate damage