NEURO - seizure medications Flashcards

1
Q

1st exemplar drug for traditional AEDs

A

PHENYTOIN

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2
Q

routes of PHENYTOIN

A

PO & IV
- IV drawn through a filter needle & given slow

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3
Q

uses for PHENYTOIN

A

control clonic-tonic & partial seziures

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4
Q

pharmacologic action of PHENYTOIN

A

inhibits influx of sodium into cells through sodium channels –> decreases activity of cells that could cause seizures

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5
Q

adverse reactions of PHENYTOIN

A
  • CNS depression
  • gingival hyperplasia
  • rash
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6
Q

nursing interventions of PHENYTOIN

A
  • monitor for excessive drowsiness
  • monitor gums for rashes
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7
Q

client education for PHENYTOIN

A
  • dont participate in activities that require mental alertness
  • get regular dental check ups
  • do not stop drug abruptly
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8
Q

interactions with PHENYTOIN

A
  • DIAZEPAM, ISONIAZID, CIMETIDINE & VALPROIC ACID: increase levels of the drug
  • alcohol can alter levels of PHENYTOIN
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9
Q

2nd exemplar drug for traditional AEDs

A

CARBAMAZEPINE

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10
Q

uses of CARBAMAZEPINE

A

controls clonic-tonic & partial seizures

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11
Q

pharmacologic action of CARBAMAZEPINE

A

inhibits influx of sodium into cells via sodium channels –> decrease activity of cells that could cause seizures

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12
Q

adverse reactions of CARBAMAZEPINE

A
  • visual disturbances
  • fluid retention
  • skin rash
  • photosensitivity
  • bone marrow suppression
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13
Q

difference between PHENYTOIN & CARBAMAZEPINE

A

PHENYTOIN side effect – CNS depression

CARBAMAZEPINE side effect – anything else lol

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14
Q

nursing interventions of CARBAMAZEPINE

A
  • monitor CBC
  • assess for rash
  • protect from sun exposure
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15
Q

client education with CARBAMAZEPINE

A
  • take with meals
  • do not mix suspension with other drugs
  • take consistently
  • do not discontinue suddenly (ween off)
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16
Q

interactions with CARBAMAZEPINE

A
  • grapefruit juice increases levels
  • decreases effectiveness of oral contraceptives & can cause false negative pregnancy tests
17
Q

exemplar drug for valproic acid

A

VALPROIC ACID

18
Q

route of VALPROIC ACID

A

PO & IV

19
Q

uses of VALPORIC ACID

A

helps to control tonic-clonic & partial seizures

20
Q

pharmacologic action of VALPORIC ACID

A
  • inhibits the influx of sodium into cells via sodium channels –> decrease of activity of cells that could cause seizures
  • CAN ALSO INHIBIT INFLUX OF CALCIUM
21
Q

adverse reactions of VALPORIC ACID

A
  • GI upset
  • bone marrow suppression (bruising, bleeding, etc)
  • hepatotoxicity
22
Q

nursing interventions of VALPORIC ACID

A

monitor for bone marrow suppression & hepatotoxicity

23
Q

client education of VALPORIC ACID

A
  • monitor for bruising, n/v & jaundice
  • follow up frequently
24
Q

interactions with VALPROIC ACID

A

increases levels of PHENYTOIN