neuro4 Flashcards

(63 cards)

1
Q

ninety percent of retinl axons terminate where

A

lateral geniculate nuc

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2
Q

PRIMARY visual cortex corresponds to brodman area what

A

brodman are 17 or striate cortex

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3
Q

brodman areas of associated visual cortex

A

18 and 19

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4
Q

in what lobes are the higher order vision processing centers

A

posterior parietal and inferior temporal cortices

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5
Q

one eye visual field loss- where is the lesion

A

optic nerve on that side

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6
Q

bitemporal visual field defect- where is the lesion

A

chiasm (because it only affects the crossing fibers, which come from the nasal portion but see the outside visual field)

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7
Q

homonymous hemianopsia- where is the lesion

A

optic tract on the opposite side OR optic radiations (both parietal and temp or meyer’s loop) on the opp side

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8
Q

homonymous quadrantonopia-where is the lesion?

A

optic radiations; parietal if lower field out and temporal or meyers loop if upper field is out

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9
Q

homonymous hemianopia with macular sparing

A

occipital cortex

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10
Q

how to detect an afferent pupillary defect

A

show light in good eye and then in bad eye; if bad eye dilates instead of constricts, that is an afferent pupillary defect

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11
Q

where do the retinal nerves synapse?

A

edinger-westphal nuc in the pretectal midbrain; it in the rostral aspect of the third nerve nuc

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12
Q

efferent parasymp fibers from edinger-westphal nuc travel with what

A

cn3

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13
Q

efferent parasymp from the EWN travel how?

A

through the cavernous sinus with the inferior divison of the third nerve and synapse in the ciliary ganglion

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14
Q

the iris contains how many muscles that regulate pupil size

A

two

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15
Q

what innervates the pupilloconstrictor?

A

parasymp fibers of the third nerve

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16
Q

what innervates pupillodilator

A

cervical sympathetic system

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17
Q

describe the path of the symp system innervating the pupillodilator of the eye

A

first order neuron to pregang to postgang

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18
Q

where is the first order neuron in symp control of the pupillodilator?

A

starts in the ipsilateral posterolateral hypothalamus (first order) then porjects down the brainstem to the intermediolateral cell column at the C8-T1 spinal level.

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19
Q

where is the second order neuron in the symp control of the pupillodilator

A

cell body at c8/t1 level and neurons synapse in the superior cervical gang;

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20
Q

where is the third order neuron for symp control of the pupil?

A

start in the superior cervical gang and neurons travel along the internal carotid artery in teh cavernous sinus and from there into the orbit to teh pupillodilator muscles

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21
Q

horner’s syndrome

A

ipsilateral miosis (small pupil), ptosis (drooping of the upper lid), inverted ptosis (elevation of lower lid), and sometimes impaired ipsilateral facial flushing and sweating (anhidrosis)

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22
Q

cocaine test

A

for horners syndrome; cocaine drops will fail to dilate the abnormal pupul

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23
Q

how does cocaine work?

A

inhibits the reuptake of norepi from the synaptic cleft

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24
Q

apraclonidine

A

weak direct acting alpha 1 and alpha 2 agonist that dilates the affected eye due to denervation supersensitivity of the iris dilator muscle

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25
hydroxyamphetamine
pupil with a postgang horners fais to dilate with this drug; distinguishes pre from postgang neuron issue
26
where is the lesion if relative afferent pupillary defect
in the eyee, optic nerve, or chiasm
27
sign of lesion in the lateral geniculate nucleus
binocular visual loss; no RAPD
28
ipsilateral smooth pursuit abnormalities and spasticity of conjugate gaze. Where is the lesion
optic radiation
29
differences in visual field defects in the temporal, parietal, or occipital lobes
temporal means superior contralateral quandrantopia; parietal is inferior contralateral quadrantopia; occipital is congruous contralateral hemianopsia with mac sparing
30
miotic versus mydriatic pupil
miotic pupil is too small and mydriatic is too big
31
characteristics of a third nerve palsy
ptosis, dilated pupil, and ophthalmoplgia
32
ophthalmoplegia
extraocular muscle palsy
33
compression of the third nerve initially causes what
dilated pupil because parasymp run on the outside; eye movements come later bc motor on the inside
34
third nerve ischemia causes what
pupil-sparing third nerve lesion in which pupil is normal but palsy of ocular muscles
35
Adie's pupil cause
interruption of the parasymp supply from the ciliary gang (cell bodies or postgang fibers)
36
adie's pupil symptoms
ansiocoria, photophobia, and blurred near vision (due to accomodation paresis)
37
adie's pupil exam
dilated pupil, poor light reaction and light-near dissociation
38
how to confirm adie's pupils
supersensitivity of the affected pupul to 0.1% pilocarpine, which will produce more contraction in the affected pupil than in the normal
39
Argyll Robertson pupil associated with what
syphilis
40
describe argyll robertson pupil
both pupils small and irregular with impaired light reaction and intact light-near dissociation; pupils dilate poorly to mydriatic agents
41
what is light near dissociation
normally pupil constricts more to light than to near things; if the opposite happens, it is called LND
42
most common symptom of optic disk swelling
transient visual obscurations, described as dimming or blacking out of visio asting a few seconds, usually ppt by changes in posture of valsalva
43
most common causes of unilateral optic disc swelling
optic neuritis; anterior ischemic optic neuropathy, and orbital compressive lesions
44
disc hemorrhage and optic disk swelling
usually anterior ischemic optic neuropathy
45
foster kennedy syndrome
ipsilateral optic disc atrophy due to compression fo the optic nerve by a space-occupying lesion in the frontal lobe and papilledema in the contralateral optic disc due to increased ICP
46
treatment for idiopathic intracranial htn
acetazolamide, nerve decompression, shunt
47
what is drusen
calcified hyaline bodies
48
asymptomatic enlarged blind spot with normal visual acuity initially
drusen
49
fundi with glistening hyaline bodies and venous pulsation
drusen
50
how to diagnoise drusen on the optic disc
CT and orbital ultrasound to see calcified hyaline bodies
51
causes of optic neuritis
demyelination (MS, SLE, adrenoeukodystrophy, sarcoidosis, tumor); behcets, viral, meningitis, whipple and crohn disease
52
painful vision loss
optic neuritis
53
Uthoff's phenomenon
worsening visual function during exercise, hot baths; assoc with optic neuritis
54
Central scotoma
classic for optic neuritis; central vision loss
55
how to diagnose optic neuritis
MRI looking for demyelination; visual evoked potentials
56
therapy for optic neuritis
IV methylprednisolone
57
if MRI of the head shows more than three demyelinating lesions, what is the prob of developing MS within 5 yr
fifty percent
58
causes of anterior ischemic optic neuropathy
carotid occlusion, embolic; TIAs; temporal arteritis
59
sudden painless vision loss
anterior ischemic optic neuropathy
60
anterior ischemic optic neuropathy associated with what other disease
hypertension, diabetes, hypotensive episodes
61
do you have relative afferent papillary defect in anterior ischemic optic neuropathy?
yes
62
CN 3 innervates what EO muscle
SR, MR, IR, levator palpebrae, pupil constrictor, and inferior oblique
63
CN3 dysfuncton
eye is down and out; ptosis; mydriasos