neurologic system part 1 Flashcards

1
Q

what does the PNS consist of?

A

cranial and spinal nerves

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2
Q

tell me about an afferent pathway

A

ascending; sensory to spinal column

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3
Q

tell me about an efferent pathway

A

descending; innervate effector organs

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4
Q

what does the somatic NS consist of and what does it control

A

motor and sensory pathways that regulate voluntary motor control of skeletal muscle

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5
Q

what does the autonomic NS consist of and what does it control

A

motor and sensory pathways that control the bodys internal environment through involuntary control of organ systems

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6
Q

what NS are the sympathetic and parasympathetic NS from

A

autonomic

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7
Q

how big are neurons

A

variable size and structure throughout the NS

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8
Q

what neurons continue to divide

A

olfactory

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9
Q

what are the cellular components of a neuron

A

microtubules, neurofibrils, and nissl substances

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10
Q

what do neurons do

A

receive, integrate, and transmit information to other cells throughout the body

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11
Q

what are the 3 main components of a neuron

A

dendrites, cell body, and axon

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12
Q

dendrites?

A

elongated processes that receive information from other neurons or the environment

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13
Q

where do axons conduct impulses

A

away from cell body

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14
Q

where is the cell body/soma located

A

mainly CNS

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15
Q

what are densely packed cell bodies in the CNS

A

nuclei

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16
Q

what are densely packed cell bodies in the PNS

A

ganglia

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17
Q

where do dendrites send impulses

A

cell body

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18
Q

axon hillock?

A

cone shaped, nissl free area where the axon leaves the cell body

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19
Q

axon initial segment?

A

area of axon with lowest threshold for stimulation so action potentials begin here

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20
Q

myelin?

A

segmented layer of lipid material that insulates the axon

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21
Q

what is myelin formed and maintained by

A

schwaan cells

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22
Q

endoneurium?

A

layer of CT around each axon

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23
Q

neurilemma?

A

thin membrane btwn myelin sheath and endoneurium

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24
Q

nodes of ranvier?

A

interruptions in the myelin sheath

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25
saltatory conduction?
flow of ions btwn segments of myelin rather than along the entire length of the axon; skips over area of demyelination
26
are nodes of ranvier myelinated or unmyelinated
unmyelinated
27
what is divergence
ability of branching axons to influence many neurons; 1 cell body and many axons
28
what is convergence
branching of numerous neurons converging on one or a few neurons
29
what happens in MS
myelin sheath is destroyed with scarring and inflammtion; autoimmune disease
30
can cells grow back their myelin
yes
31
how are nuerons classified
structural; based on the number of processes extending from the cell body
32
3 types of neurons?
bipolar, multipolar, pseudounipolar
33
what type of neurons are motor neurons
multipolar
34
what type of neurons are sensory neurons
pseudounipolar
35
what neurons have 2 processes attached to an oval shaped cell body
bipolar
36
what does one process of the bipolar neuron function as? what does the other do?
1: dendrite which carries information from the periphery of the organism 2: axon carrying information towards the CNS
37
where are bipolar neurons found
retina of the eye and olfactory epithelium of the nose
38
which neurons are specialized?
bipolar because they are in the retina of the eye and olfactory epithelium of the nose
39
what neuron type is the main one in the mammalian CNS
multipolar
40
what does a multipolar neuron look like
single axon and multiple dendrites emerging from the cell body; vary in size, number, and length of processes depending on number of synaptic contacts they make with other neurons
41
what NS are pseudounipolar neurons located in
peripheral
42
where are pseudounipolar neurons located
cranial and spinal nerves
43
what does a pseudounipolar neuron look like
dendritic portion extends away from the CNS and axon portion projecting into the CNS
44
which cells in the NS are the nerve glue
neuroglia
45
what do neuroglia do?
support neurons of CNS and PNS
46
types of neuroglia?
astrocytes, oligodendroglia, microglia, and ependymal cells
47
which type of neuroglia has "end feet"
astrocytes
48
what do "end feet" connect to
BV in brain
49
what do "end feet" do?
regulate local blood flow to provide oxygen and nutrients to neurons in need
50
besides having end feet that regulate blood flow, what else do astrocytes do
release NT to neighboring neurons
51
who do astrocytes interact with?
several neurons and hundreds of thousands of synapses to properly integrate info
52
which neuroglia have metabolic, immunologic, structural, and nutritional functions?
astrocytes
53
what are microglia derived from
bone marrow precursors of monocytic lineage
54
what is the main effector cell in the CNS
microglia
55
what are microglia activated by
brain injury, infection, neuronal degeneration
56
where do microglia reside
brain
57
when microglia are activated what do they do
produce cytokines, upregulate MHC, proteinase production, and ROS
58
what do ROS do
remove dead tissue and destroy invading organisms and contribute to CNS damage
59
what are synapses
regions btwn adjacent neurons or a neuron and a muscle that allow them to communicate with one another
60
how are impulses transmitted across synapse
chemical and electrical conduction
61
what type of synapse deals with action potentials
electrical synapses
62
what type of synapse deals with NT
chemical synapses
63
what does an excitatory synapse do
increases probability the postsynaptic neuron will fire or that the muscle will move
64
what does an inhibitory synapse do
decreases probability the postsynaptic neuron will fire or inhibits motor function
65
where does the presynaptic neuron send information
postsynaptic
66
which synapses stop communication
inhibitory
67
what do NT act on
muscles
68
synaptic cleft
region btwn axon and motor end plate
69
what do vescicles do
pass NT from presynaptic membrane into synaptic cleft
70
how do vesicles release NT
exocytosis
71
where are Ach NT located?
neuromuscular junction, autonomic ganglia, parasympathetic neurons, motor nuclei of cranial nerves, caudate nucleus and putamen, basal nucleus of meynert, parts of lymbic system
72
where are NE NT located?
sympathetic NS, locus ceruleus, lateral tegmentum
73
where are dopamine (DA) NT located?
hypothalamuc and midbrain nigrostriatal system
74
where are serotonin (5-HT) NT located?
parasympathetic neurons in GUT, pineal gland, nucleus raphe magnus of pons
75
where are gamma-aminobutyric acid (GABA) NT located?
cerebellum, hippocampus, cerebral cortex, striatonigral system
76
where are glycine NT located?
spinal cord
77
where are glutamic acid NT located?
spinal cord, brain stem, cerebellum, hippocampus, cerebral
78
which hormone is the pleasure hormone
dopamine
79
which NT helps with GI issues
serotonin (5-HT)