neuromuscular disorders Flashcards
1
Q
presynaptic disorders
A
botulism
lambert-eaton myasthenic syndrome
2
Q
botulism
A
rare
caused by clostridium botulinum
rapid onset weakness without sensory loss
3
Q
lambert eaton myasthenic syndrome
A
antibodies to presynaptic calcium channels lead to less vesicle release
strong underlying with small cell carcinoma
4
Q
treatment of lambert-eaton myasthenic syndrome
A
3-4 diaminopyridine
5
Q
presentation of myasthenia gravis
A
fatigable weakness of skeletal muscle
most common presentation with extraocular weakness, facial and bulbar weakness
proximal limb weakness
6
Q
diagnosis of myasthenia gravis
A
serum ACh
single fibre EMG
always CT chest
7
Q
acute treatment of myasthenia gravis
A
acetylcholinesterase inhibitor-pyridostigmine
intravenous IG
thymectomy
