tumours

Question 1

treatment of grade II astrocytomas

Answer 1

surgery +/- radiation, chemo, combined depending on molecular profile

Question 2

glioblastoma multiforme

Answer 2

most common primary tumour
median survival one year

Question 3

treatment of malignant astrocytomas

Answer 3

noncurative surgery: cytoreduction, reduce mass effect
post operative radiotherapy

Question 4

how to differentiate between oligodendroglial tumours and atrocytomas

Answer 4

oligodendroglial tumours have calcification, cysts, peritumoral haemorrhage

Question 5

grading of oligodendroglial tumours

Answer 5

low grade
anaplastic/astrocytic component

Question 6

treatment of oligodendroglial tumours

Answer 6

chemosensitive: procarbazine, lomustine, vincristine
surgery +chemo
radiotherapy

Question 7

tumour markers for midline brain tumours in a child

Answer 7

alpha-fetoproten, bHcG and LDH

Question 8

pleomorphic tumour cells border necrotic areas

Answer 8

glioblastoma multiforme