Neurotransmitters: deck 1 (Unit 3) Flashcards

(61 cards)

1
Q

What are the three classes of neurotransmitters?

A

Amino Acids
Monoamines
Acetylcholine

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2
Q

What are the four main amino acid neurotransmitters?

A

Glutamate
Aspartate
GABA
Glycine

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3
Q

What are the four monoamines?

A

Dopamine
Norepinephrine
Epinephrine
Serotonin

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4
Q

What type of neurotransmitter is Glutamate?

A

Amino Acid

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5
Q

What type of neurotransmitter is Aspartate?

A

Amino Acid

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6
Q

What type of neurotransmitter is GABA?

A

Amino Acid

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7
Q

What type of neurotransmitter is Glycine?

A

Amino Acid

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8
Q

What type of neurotransmitter is Dopamine?

A

Monoamines

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9
Q

What type of neurotransmitter is Epinephrine?

A

Monoamines

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10
Q

What type of neurotransmitter is Norepinephrine?

A

Monoamines

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11
Q

What type of neurotransmitter is Serotonin?

A

Monoamines

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12
Q

What three neurotransmitters are Catecholamines?

A

Dopamine
Epinephrine
Norepinephrine

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13
Q

What neurotransmitter is an indolamine?

A

Serotonin

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14
Q

What neurotransmitters are synthesized from Tyrosine?

A

Dopamine
Epinephrine
Norepinephrine
(all catecholamines)

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15
Q

What is Catecholamine synthesis?

A

The synthesis of Dopamine, Epinephrine, and Norepinephrine from Tyrosine

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16
Q

What is the order of Catecholamine synthesis?

A

Tyrosine -> L-dopa -> Dopamine -> Norepinephrine -> Epinephrine

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17
Q

What is the precursor molecule to Epinephrine, Norepinenphorine, and Dopamine?

A

Tyrosine

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18
Q

What is Tyrosine?

A

The precursor molecule to Dopamine, L-dopa, Norepinephorine, and Epinephorine.

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19
Q

What neurotransmitter is synthesized by Tryptophan?

A

Serotonin

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20
Q

What is Serotonin synthesis?

A

The synthesis of serotonin from tryptophan

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21
Q

What is the order of Serotonin synthesis?

A

Tryptophan -> 5-HT -> Serotonin

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22
Q

What is 5-HTP?

A

The precursor molecule to serotonin

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23
Q

What is the precursor molecule to serotonin?

A

Tryptophan, and 5-HTP

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24
Q

What is Tryptophan?

A

the precursor molecule to Serotonin

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25
What neurotransmitter has its own classification because it is acetylated?
Acetylcholine
26
What is Acetylcholine's primary function?
playing a role in muscle contraction
27
What are the two main unconventional gaseous neurotransmitters?
Nitric oxide (NO) and Carbon monoxide (CO)
28
What small nonpolar molecules traverse the cell membrane of a neuron?
Nitric oxide (NO) and Carbon monoxide (CO)
29
What is the role of NO and CO molecules?
they move from neurons to other cells and stimulate the production of second messenger molecules
30
What neurotransmitters stimulate the production of second messenger molecules?
Nitric oxide (NO) and Carbon monoxide (CO)
31
Nitric oxide and Carbon monoxide are short-lived molecules. True or False
True
32
What neurotransmitter molecules are involved in Retrograde transmission?
Nitric oxide (NO), Carbon monoxide (CO), and endocannabinoids
33
What is an Endocannabinoid?
an unconventional class of neurotransmitter
34
What is a neuropeptide?
large unconventional neurotransmitters, that are polypeptide chains that are sometimes protein, each carrying a specific function depending on its amino acid sequence
35
How are neuropeptides categorized?
primarily by their location in the body
36
What are the five main neuropeptides?
Pituitary peptides, hypothalamic peptides, brain-gut peptides, opioid peptides, and miscellaneous
37
Where are pituitary neuropeptides located?
pituitary gland
38
Where are hypothalamus neuropeptides located?
hypothalamus
39
Where are brain-gut neuropeptides located?
gut
40
Where are opioid neuropeptides located?
resemble opium
41
What response occurs when a neurotransmitter binds to its active site?
either cause excitation or inhibition
42
What does excitation result in for the postsynaptic neuron?
(propagates a signal) depolarization of the neuron
43
What does inhibition result in for the postsynaptic neuron?
(halts a signal) hyperpolarization of the neuron
44
What must occur for the propagation of a signal in a postsynaptic neuron?
excitation/depolarization
45
What must occur for the halt of a signal in a postsynaptic neuron?
inhibition/ hyperpolarization
46
What signal does Glutamate typically produce?
excitatory/ depolarization
47
What signal does Glycine typically produce?
Inhibition/ hyperpolarization
48
What signal does GABA typically produce?
Inhibition/ hyperpolarization
49
What signal does Acetylcholine typically produce?
either excitatory or inhibitory
50
When is Acetylcholine excitatory?
at the neuromuscular junction of skeletal muscles
51
When is Acetylcholine inhibitory?
at the neuromuscular junction of cardiac muscles
52
What is direct action?
when neurotransmitter binding causes receptors to open up so that ions can pass through
53
When a neurotransmitter binding causes receptors to open up so that ions can pass through it is called
direct action
54
Which type of action directly affects membrane potential, propagating a specific effect? direct action Indirect action
direct action
55
What neurotransmitters tend to exhibit direct action behavior?
Acetylcholine and Amino Acids: (Glutamate Aspartate GABA Glycine)
56
What is indirect action?
when action is promoted through second messenger molecules like G-protein
57
When action is promoted through second messenger molecules like G-protein it is called
indirect action
58
Which type of action operates similarly to hormones? direct action indirect action
indirect action
59
Which type of action is mediated by metabotropic receptors? direct action indirect action
indirect action
60
What neurotransmitters tend to exhibit indirect action behavior?
monoamines: (Dopamine, Norepinephrine, Epinephrine, Serotonin) neuropeptides Small gas molecules: (NO, CO)
61
What are neuromodulators?
neurotransmitters that exhibit indirect action behavior