Non-neoplastic bone disease Flashcards Preview

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Flashcards in Non-neoplastic bone disease Deck (19):
1

Gout: what is it? epidemiology?

A type of arthritis in which a high uric acid blood level eventually results in deposition of needle like urate crystals.
epidemiology - middle aged males

2

Gout aetiology (4)

High purine diet
ETOH
Diuretics
Rare genetic metabolic abnormalities

3

Gout Joints affected (2) & clinical features (2)

Usually great toe - MTP (podagra)
Lower extremeties e.g. knee
Clin features - red, hot, painful swollen joint.
TOPHUS (sub cut urate deposits) are pathognomic e.g. in pinna/ hands

4

Gout crystal type (1) Ix (1)

Urate crystals - needle like
Ix - negatively birefringent crystals

5

Gout management: acute (1), long term (1), conservative (2)

Acute - colchocine
chronic - allopurinol
conservative - low ETOH & low purine diet e.g. sardines & liver

6

Pseudogout: what is it? epidemiology (1)

A type of arthritis where get calcium pyrophosphate crystals depositied in joints.
> 50yrs

7

Pseudogout: aetiology (4), joints affected (2)

Idiopathic
Wilsons
DM
HyperPTH
Hypothyroid
Knee & shoulder joints

8

Pseudo gout clin features (2) crystal type (1)

Hot swollen joint, w/ effusion
Calcium pyrophosphate crystals (rhomboid shaped)

9

Pseudogout Ix (1) management (1)

Poitively birefringent
NSAIDS or intra-articular steroids

10

Types of fractures (5)

Simple
Compound
Greenstick
Comminuted
impacted

11

Fracture repair (4)

1. Organization of haematoma - pro callus
2. Formation of fibrocartillaginous callus
3. Mineralisation of fibrocartillaginous callus
4. Remodeling of bone along weight bearing lines

12

Influences on fracture healing (6)

Fracture type
neoplasm
drugs
metabolic disorder
vit def
infection

13

Osteomyelitis - adults: most common organism, common areas (3)

S. Aureus
Vertebrae
Jaw - secondary to dental abscess
Toes - due to diabetic skin ulcer

14

Osteomyelitis - Children: most common pathogens (2), common areas (1)

Haemophilus influenza
GBS
Long bones

15

Presentation of Osteomyelitis (5)

Pain
swelling, tenderness
Features of malaise
fevers
leukocytosis

16

Osteomyelitis x-ray changes (1), Rare causes (2)

Lytic destruction of bone - seen 10 days post-onset
TB
Syphils

17

Osteoarthritis: what is it? What signs (nodes) may be seen? (2)

Degenerative joint disease mainly affecting vertebrae, hips, knees
Herberden's nodes (DIPJ)
Bouchard's nodes (PIPJ)

18

RA: clinical presentation (2),

Usually slow progressing course
Symmetrical
Small joints affected of hand and feet - wrists, elbows, ankles, knees - SPARING DIPJ

19

RA: Characteristic deformities (3)

Radial deviation of wrist & ulnar deviation of fingers
"swan neck" & "boutonniere" deformity of fingers
Z shaped thumb