Nucleic Acid Protien Synthesis Flashcards
(27 cards)
Nucleic acid
DNA and RNA
Amino Acids
Really small things that make up a polypeptide
What is a polynucleotide
A bunch of nucleotides put in a line, DNA and RNA!
Parts of a nucleotide
Phosphate, sugar, nitrogenous base
What is the nucleoside?
The side of the nucleotide without the phosphate (the sugar and the nitrogenous base)
Pyrimidines vs Purines, how many rings?
Pyrimidine: 1
Purine: 2
Which are the Pyrimidines
Cytosine (C) and Thymine(T)/Uracil(U)
Which pyrimidine is in DNA?
Thymine (T)
Which pyrimidine is in RNA?
Uracil (U)
Which sugar is in DNA?
Deoxyribose (H in 2’)
Which sugar is in RNA?
Ribose (OH in 2’)
What is the backbone of DNA/RNA?
Sugar-phosphate backbone
The two polynucleotides (The strands of DNA) run…
Antiparallel
Which are the purines?
Adenine (A) and Guanine (G)
What is the shape DNA takes?
Double helix
What are all the nitrogenous bases?
Cytosine, Thymine, Uracil, Adenine, Guanine
What are Chargaff’s rules?
- DNA base composition varies between species
- For DNA, the amout of A and T bases match, and the amount of G and C match
What does it mean that DNA replication is ‘semiconservative’?
The two strands of DNA seperate and act as a template for their new partner (complimentary) strand. Each parental strand is now paired with a daughter strand.
Helicase
Untwist DNA at the replication forks and separate the parental strands
Single-strans binding protien
Stabilizes the unwound parental strands
Primase
Synthesizes RNA primers, using the parental DNA as a template
What ar the segments of lagging strands called?
Okazaki fragments
During DNA replication, what adds nucleotides to the new strands
DNA polymerase III (3)
What follows behind a DNA polymerase III?
Sliding clamp