Uses
Xontrol deities and stays epilepticus
Reduce frequency of general and focal seizures
Moa
Reduce neuronal excitability
Binds NA Chanel receptor to prevent na influx and prevent threshold for AP Being met
Se
Phenytoin
P 45 Inducer Hruiisman acne Enlarged gums Nystagmus Yellow of skin Tetrogenic Osteomalacia Inhibit metabolism of b12 Neuropathy ataxia and vertigo
Ci
Pregnancy phenytoin syndrome in babies craniofacial malformations
Liver disease
Drug interactions
Warfarin reduce effect
Metabolism byb0450 itself therefore with p450 inducers or inhibitors can impair its impact
Efficacy reduces by drugs which lower seizure threshold