Onc

Question 1

Ph Chromosome =

Answer 1

CML

also Bcr-Abl mutation

Question 2

Which med treats CML?

Answer 2

Gleevec

Decreases risk for crisis de la blasts

Question 3

African americans and pacific islanders are at higher risk for which blood dz?

Answer 3

MM

Question 4

Monoclonal protein, roleaux formation =

Answer 4

MM

Question 5

Most common adult leukemia?

Answer 5

CLL

affects B lymphocytes

Question 6

smudge cells =

Answer 6

CLL

Question 7

Which blood dz is hydroxyurea and asa used to tx?

Answer 7

PV

Question 8

Cisplatin causes?

Answer 8

Renal tox

Question 9

Which med causes ruby red urine?

Answer 9

Adriamycin

Question 10

Which drug treats B-cell NHL

Answer 10

Rituximab

Cardiotoxic

Question 11

Ipilimubab causes?

Answer 11

Endocrine failure

No cortisol

Question 12

Cytoxan (cyclophosphamide) causes?

Answer 12

Hemorrhagic cystitis

Question 13

Vincristine causes?

Answer 13

Peripheral Neuropathy

Question 14

Does DCIS affect one or 2 breasts?

Answer 14

Always one

Question 15

Infiltrating ductal carcinoma

Answer 15

Most common type of invasive BCA

Question 16

Which therapy is used for ER/PR tumors?

Answer 16

Tamoxifen

Question 17

What is used for HER2 BCA?

Answer 17

Trastazumab

Question 18

Doxyrubicin causes?

Answer 18

Cardiac complications

Question 19

Bleomycin causes?

Answer 19

Pulmonary fibrosis

Question 20

What is a SE of tamoxifen

Answer 20

blood clots

Question 21

Which ovarian CA occurs in younger women?

Answer 21

Germ Cell

Question 22

What is the most common ovarian CA in older women?

Answer 22

Epithelial

Question 23

Tests for ovarian CA

Answer 23

CA-125 and HE4

Question 24

BRCA genes are associated with which cancers?

Answer 24

Breast and Ovarian

Question 25

Is radiation used for ovarian CA?

Answer 25

No

Question 26

Most common GYN CA in the US?

Answer 26

Endometrial

Question 27

Type 1 Adenocarcinoma

Answer 27

Estrogen sensitive Endometrial CA Good prognosis Most common

Question 28

Progestin

Answer 28

If added to hormone replacement therapy, lowers risk of endometrial CA.

Question 29

HNPCC

Answer 29

Hereditary non-polyposis Colorectal cancer Lynch syndrome Runs in families

Question 30

Squamous cell cervical CA

Answer 30

Most common type

Question 31

What causes cervical CA?

Answer 31

HPV 16, 18, 45

Question 32

Which blood dz usually causes leukostasis?

Answer 32

AML

Question 33

Breast and lung cancer can release which hormone?

Answer 33

PTHrP | Hypercalcemia ensues

Question 34

Small cell lung cancer secretes?

Answer 34

SIADH

Question 35

Hypotension JVD Muffled heart sounds

Answer 35

Becks triad of cardiac tamponade

Question 36

A smoker with hyponatremia

Answer 36

SIADH from SCLC

Question 37

What kind of bone lesions does breast CA make?

Answer 37

Lytic bone lesions

Question 38

Ewing lesions are lytic or blastic?

Answer 38

lytic then blastic

Question 39

Benign lesions of skeletal long bones. Knee and shoulder are common. Most common skeletal neoplasms.

Answer 39

Osteochondroma

Question 40

What type of bone lesions does prostate CA make?

Answer 40

Osteoblastic

Question 41

Most common primary bone tumor?

Answer 41

MM

Question 42

Which sites met to bone?

Answer 42

``` Breast Prostate Lung Kidney Thyroid ```

Question 43

Most common bone malignancy in kids

Answer 43

Osteosarcoma Long bones Males in 2nd decade

Question 44

Lytic lesion of the pelvis or long bones with onion skin and blue cells?

Answer 44

Ewing sarcoma

Question 45

Axial skeleton tumors in adults that are slow growing and metastasize to lungs?

Answer 45

Chondrosarcoma | Also have stippled calcification

Question 46

AFP detects?

Answer 46

Liver and germ cell CA

Question 47

Beta hCG detects?

Answer 47

Choriocarcinoma and Testicular CA

Question 48

CA 19.9

Answer 48

Pancreatic, bile duct, gall bladder, gastric CA

Question 49

CA 125

Answer 49

Ovarian CA

Question 50

CEA

Answer 50

Colorectal and Breast CA

Question 51

Calcitonin

Answer 51

Medullary thyroid CA

Question 52

Reed sternberg cell =?

Answer 52

Hodgkin Lymphoma

Question 53

Sunburst pattern, codman's triangle

Answer 53

Osteosarcoma