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Flashcards in Oncology Deck (57)
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1

best initial test breast cancer

biopsy

2

which type of biopsy is the best initial for breast cancer

FNA

3

FN rate of FNA for breast cancer

10%

4

core needle biopsy

LARGER SAMPLE, more deforming, ER/PR/HER2/Neu; possibility that needle will miss the lesion

5

most ACCURATE bx type for breast cancer

open biopsy-- frozen section while in operating room; followed by immediate resection of cancer, followed by sentinel node bx

6

mammography screening-- age start at

50yo

7

NB even if already getting FNA

do MAMMOGRAPHY -- since 5-10% of patients = bilateral

8

MRI use for breast cancer

PRECISE USE NOT clear yet;
young woman with dense breasts

9

US breast cancer

indeterminant mass lessions
cystic vs. solid
if the lesion is PAINFUL
or VARIES in size/pain with MENSES

10

PET scan breast cancer

determine CONTENT of abnormal lymph nodes that are not easily accessible to biopsy

11

BRCA testing

a.w increased risk of breast cancer

12

other cancers a/w BRCA

PANCREATIC and OVARIAN cancer

13

BRCA positive... now what

WILL NOT BE ASKED--since NOT yet shown to add mortality benefit to usual mgmt;
(most go for bilateral mastectomy)

14

sentinel lymph node biopsy

done AT THE TIME of lumpectomy/mastectomy

15

negative sentinel node

ELIMINATES NEED FOR axially lymph node dissection

16

RADIATION for breast cancer

INDISPENSIBLE in preventing cancer RECURRENCES

17

premenopausal option of hormone manipulation breast cancer

tamoxifen

18

postmenopausal option of hormone manipulation breast cancer

aromatase inhibitors

19

letrozole

aromatase inhibitor

20

exemestane

aromatase inhibitor

21

side effect of aromatase inhibitors

OSTEOPOROSIS

22

RADICAL MASTECTOMY

ALWAYS the wrong answer

23

trastuzumab...

DECREASES risk of recurrent disease
INCREASES survival

24

adjuvant chemotherapy for breast cancer

- lesions > 1 cm
- positive axillary nodes are found

25

use tamoxifen when ...

multiple FDR's have breast cancer,
LOWERS RISK of breast cancer

26

lowering mortality

- mammography
- ER/PR testing, then tamoxifen/raloxifene
- aromatase inhibitors
- adjuvant CHEMO
- LUMPECTOMY and RADIATION
- modified radical mastectomy
- TRASTUZUMAB (anti-Her 2/neu)
- prophylaxis with tamoxifen/ raloxifene

27

best initial test for prostate cancer

BIOPSY

28

which is better for survival

prostatectomy MAY SLIGHTLY benefit more than radiation

29

complications of prostatectomy

erectile dysfunction
urinary incontinence

30

erectile dysfunction more likely post-prostatectomy OR radiation

post-prostatectomy