One Liners Set 04

Question 1

Anti-bacterials that cause hemolysis in G6PD-deficient patients

Answer 1

Sulfonamides

Question 2

Why are benzodiazepines used with caution during pregnancy?

Answer 2

They can cross the placenta

Question 3

Substance that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol-oxidizing system (MEOS)

Answer 3

Ethanol

Question 4

System that increases in activity with chronic exposure to alcohol; may contribute to tolerance

Answer 4

Microsomal ethanol oxidizing system (MEOS)

Question 5

The most common neurologic abnormalities in chronic alcoholics

Answer 5

Neuropathy (peripheral)*
HTN
Anemia
MI

Question 6

Drugs of choice for generalized tonic-clonic and partial seizures

Answer 6

Valproic acid
Phenytoin
Carbamazepine

“Val’s Phender on her Car is seizing”

Question 7

Drugs of choice for absence seizures

Answer 7

Ethosuximide
Valproic acid

“Sux to be Val. She’s always absent.”

Question 8

Drug of choice for myoclonic seizures

Answer 8

Valproic Acid [DEPAKOTE]

Question 9

Anti-seizure drugs used also for pain of neuropathic origin

Answer 9

Gabapentin [NEURONTIN]

Question 10

SE’s of Phenytoin

Answer 10

Diplopia
Ataxia
Nystagmus
Gingival hyperplasia

Question 11

DOC for malignant hyperthermia that acts on the sarcoplasmic reticulum or skeletal mm.; may be caused by use of halogenated anesthetics

Answer 11

Dantrolene

Question 12

Opioid associated with awareness during surgery and post-operative recall, but still used for high-risk cardiovascular surgeries

Answer 12

Fentanyl [DURAGESIC]

Question 13

Disorder caused by Antipsychotics, Reserpine at high doses, and MPTP (by-product of illicit meperidine analog); Irreversible

Answer 13

Drug-induced Parkinsonism

Question 14

Side effects of antipsychotics that block dopamine

Answer 14

HyperProlactin-emia
Amennorrhea
Neuroleptic malignant syndrome
Galactorrhea
Extrapyramidal Symptoms (EPS)

“If you’re psychotic and don’t have DA, you have to cHANGE”

Question 15

Antipsychotics with the strongest autonomic effects

Answer 15

Chlorpromazine
Thioridazine

“Only a Pro Rida can drive that strong auto”

Question 16

Agent with greater affinity to 5HT2A receptor; reserved for refractory schizophrenia; can cause weight gain and agranulocytosis

Answer 16

Clozapine

Schizophrenia pts. just won’t “CLOZ” their mouths. (so they talk a lot and “eat a lot”)

Question 17

Anti-psychotics shown NOT to cause Tardive Dyskinesia

Answer 17

Clozapine
Quetiapine

“Cloz your mouth to keep Quiet”

Question 18

Side Effect of lithium treatment in pts. who are dehydrated/concurrently taking diuretics

Answer 18

Lithium toxicity

Lithium-induced Nephrogenic Diabetes Insipidus

Question 19

DOC for Bipolar Affective Disorder

Answer 19

Lithium

Question 20

Side Effects of Lithium

Answer 20

Ataxia & Aphasia
Diabetes InSipidus (reversible) &
Sedation
Tremor and Thyroid enlargement

Question 21

Tricyclic Antidepressant (TCA) used in treatment of chronic pain, enuresis, and OCD

Answer 21

Imipramine

Question 22

Unicyclic antidepressant used for management of nicotine withdrawal; Side Effects: dizziness, dry mouth, psychosis aggravation, seizures;Least likely to affect sexual performance

Answer 22

Bupropion [WELLBUTRIN]

Question 23

Tolerance to all effects of opioid agonists can develop, except the following effects

Answer 23

Miosis
Convulsions
Constipation

Question 24

Opioid used in the management of withdrawal states

Answer 24

Methadone

Question 25

Opioid available trans-dermally

Answer 25

Fentanyl [DURAGESIC]