Opiate Abuse, MacIntyre Flashcards Preview

Year 2 Psych exam2 > Opiate Abuse, MacIntyre > Flashcards

Flashcards in Opiate Abuse, MacIntyre Deck (34):
1

how many people die everyday from opioid OD

44

2

which drug is on the rise in OD

heroin

3

leading cause injury death in 2013

drug OD

4

deadly combo of drugs

benzos and opioid painkillers

5

routes of opium

PO, IV, skin pop, snort, smoke

6

most popular Rx opioids

OxyContin:oxycodone
Vicodin: hydrocodone/acetaminophen
Percocet: oxycodone acetaminophen

7

Sx of Rx opioids

euphoria, sedation
constricted pupils
slurred speech
impaired coordination
dec BP HR and rspiratory depression

8

other names for heroin

horse, dope, H, junk, smack

9

how is heroin used

IV IM snorted skin popping

10

Sx heroin

euphoria, sedation, constricted pupils, impaired coordination, can cause dec BP HR, respiratory depression

11

IV use heroin inc risk for

HIV
HCV
HBV
cellulitis
sepsis
bacterial
endocarditis

12

Street heroin cut with

sometimes fentanyl, barbs, household powders... etc

13

intoxication Sx of heroin

pupillary constriciton
flushing
sedation
slurred speech
bradycardia
hypotension
resp depression
hypothermia
constipation

14

withdrawal Sx of heroin

pupillary dilation
piloerection
nausea
vomiting
diarrhea
lacrimation
rhinorrhea
joint/muscle pain
abdominal cramps
yawning

15

withdrawal heroin peaks

3-4 days
can continue for weeks to months

16

if patient has co morbid respiratory conditions

avoid opiate use, at least reduce dose

17

naloxone

reverse opiate OD
shown in like epi pen format or intranasal

18

first step Tx for opioid abuse

detox

19

types of detox

cold turkey
methadone and wean
buprenorphine
supportive meds for withdrawal Sx
clonidine for mild withdrawal or as adjunct

20

after detox

need to transition to maintenance Tx else at high risk of relapse

21

synthetic opioid

methadone

22

pros methadone

safety
safe in pregnancy
intoxicating effects less euphoric
can take at home

23

cons to methadone

cant leave clinic vicinity for a day
prolong QT
multiple DDI
use restricted

24

What is LAAM

levo alpha acetylmethadol
similar to methadone but less dosing

25

buprenorphine

high affinity for opioid R mu and kappa

26

Side effects buprenorphine

nausea and vomiting

27

buprenorphine abuse

IV
can be fatal

28

what is suboxone

buprenorphine/naloxone

29

MOA buprenorphine

partial agonist, quick onset, prevents binding to other opiates

30

how is subloxone laken

sublingually

31

what happens with crushed or injected suboxone

patient goes into withdrawal

32

naltrexone

synthetic opiate antagonist

33

warnings with naltrexone

hepatotoxic

34

when giving naltrexone must require patient to carry

alert card notifying medical personnel that they are on opiate antagonist and higher doses may be needed to overcome blockade