Flashcards in Opiates Deck (16):
What are opioids also known as?
narcotics - those that induce "addiction"
What is the opioid mode of action?
reversible combination with one or more specific receptors in the brain and spinal cord
What are five effects of opioids?
What are the four opioid groups?
opioid agonists, partial agonists, agonist-antagonists, or antagonists
What are five opioid agonists?
What is one opioid partial agonist?
What four opioids have the strongest analgesic effect?
What are four opioid agonist/antagonists?
What is one opioid antagonist?
What opioid cardiopulmonary effects may occur?
Respiratory depression is dose dependent
Apnea possible at higher doses
What opioid GI effects may occur?
Vomiting in species that can
What opioid CNS effects may occur?
Depression – dogs – excellent sedation
Excitement – esp. cats & horses
Analgesia – before, during, or after surgery
Decreased body temp – esp. dogs – panting – resets temp regulating center
Decreased urine production
Excessive sweating – horses
Cough suppression – Butorphenol, hydrocodone
Miosis in dogs and pigs; mydriasis in cats and horses
Increased response to sensory stimuli
May or may not lose consciousness
Responsive to auditory stimuli
Many defecate/some vomit/flatulence
Sedation-analgesia; ataxia &/or recumbency
Decreased ventilation/apnea may occur
Bradycardia – premed. To prevent
Behavioral abnormalities – after procedure
Some breeds i.e. Dobermans
A state of CNS depression and analgesia produced by the combination of a tranquilizer or sedative and an analgesic drug
Useful in dogs, cats, horses, pigs
What is an example of Neuroleptanalgesia drug cocktail?
Fentanyl + Droperidol
Useful for short operative procedures
What effect do NSAIDS have?
Decrease inflammation/produce analgesia
Not on the scale of opioids