Oral Cavity and Sinuses Flashcards Preview

MODHIII - Unit 3 > Oral Cavity and Sinuses > Flashcards

Flashcards in Oral Cavity and Sinuses Deck (48)
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31

Mucoepidermoid carcinoma: site, microscopic

- site: parotid & minor salivary glands
- microscopic: mucus cells & squamous epithelial cells

32

Mucoepidermoid carcinoma: how to tell it involves squamous cells

- intercellular bridges

33

Mucoepidermoid carcinoma: special stain

- mucicarmine stain: stains for mucus

34

Mucoepidermoid carcinoma: differentiation epithelial cell atypia

- high epithelial cell atypia = high grade tumor

35

Mucoepidermoid carcinoma: behavior

- depends on degree of differentiation
- low grade >90%, 5 years; high grade 20-40%, 5 years

36

Adenoid cystic carcinoma: site, microscopic, behavior

- site: major and minor gland, myoepithelial cells participate
- microscopic: cribiform pattern, "swiss cheese", **perineural invasion**
- behavior: indolent course often marked by recurrence

37

Adenoid cystic carcinoma: treatment

- surgical removal, with attention to free margins and negative margins of nerves
- indolent course marked by recurrence, tumor is often fatal, but fatalities may occur 15-20 years after initial presentation
***recurrences related to PERINEURAL invasion***

38

Acinic cell carcinoma: site, microscopic

- site: parotid
- microscopic: recreates salivary gland acinus

39

Acinic cell carcinoma: histological features

- no duct structures
- Zymogen granules

40

Acinic cell carcinoma: treatment, behavior

- treatment: surgical removal, attention to free margins
- behavior: slow growing, 80-90% 5 years

41

Paranasal sinus: inflammatory reaction

- allergic rhinitis

42

Allergic rhinitis (hay fever)

- many allergens responsible, pollens
- IgE mediated
- repeated exposure--thick mucosa, nasal/sinus polyps

43

Nasal sinus - fungal diseases

- invasive fungal sinusitis
- allergic fungal sinusitis
- fungus ball

44

Invasive fungal sinusitis

- aspergillus or mucorales (BAD) species
- seen in immunocompromised, hematologic malgnancies, diabetic ketoacidosis
- vascular invasion by fungi common resulting in necrosis and hemorrhage

45

Invasive fungal sinusitis: course, treatment

- course: fatal infection many times b/c of extension into brain
- treatment: immediate surgical removal of infected tissue

46

Allergic fungal sinusitis: definition, presentation, histology

- altered immune response to fungal agents (atopic)
- rhinorrhea, pressure in sinus, headaches
- histology: mucin, EOSINOPHILS, degenerated epithelial cells

47

Allergic fungal sinusitis: organisms

- Aspergillus
- Dematiaceous: alternaria, bipolaris, curvularia (ABC-D)

48

Fungus ball

- unilateral sinus obstruction and pain
- masses of fungal organisms in sinus (aspergillus species)
- treatment: removal of fungal mass