OWEL EVALS PRELIMS (2022)

Question 1

What is true about pH?

Answer 1

Negative log of Hydrogen

ion concentration

Question 2

What is true about bases?

Answer 2

dissociates completely even

at high PH

Question 3

Possible isomers of glycoside with 5

chiral carbon?

Answer 3

32

Question 4

Etiology of metabolic acidosis

Answer 4

Diarrhea

Question 5

Water is an

Answer 5

excellent nucleophile

Question 6

What is true about

glycosaminoglycan?

Answer 6

Attached to protein
molecule from
proteoglycan

Question 7

Angle of water

Answer 7

105 degrees

Question 8

What is the primary compensation of

respiratory acidosis?

Answer 8

metabolic alkalosis
(increase pH, increase
HCO3)

Question 9

What is the primary compensation of

metabolic acidosis?

Answer 9

respiratory alkalosis

decrease CO2

Question 10

Which has molybdenum and
plays important role in converting
purine to uric acid?

Answer 10

Xanthine oxidase

Question 11

What is the dielectric constant

of water?

Answer 11

78.5

Question 12

What is the prosthetic group of

glutathione peroxidase?

Answer 12

Selenium

Question 13

wo glucose molecules (alpha

1,1)

Answer 13

Trehalose

Question 14

Coulomb’s Law

Answer 14

soul searching nalng sa book daw

Question 15

Entire complement of sugar of

an organism

Answer 15

Glycome

Question 16

Same molecular formula as

glucose with keto group position 2?

Answer 16

Fructose

Question 17

Which of the ff has low GI

Answer 17

Vegetable

Question 18

Which is true about glycolysis?

Answer 18

Irreversible step

Question 19

Which is the greatest
quantitative source in aerobic
organisms?

Answer 19

Oxidative phosphorylation

Question 20

Which helps/works with

invertebrate muscle

Answer 20

Arginine phosphate

Question 21

Which of the ff is true about

acids?

Answer 21

Proton donors

Question 22

What do you call glucose

epimer at carbon 2?

Answer 22

D-mannose

Question 23

Glucose epimer at Carbon 4?

Answer 23

D-galactose

Question 24

Uses hydrogen as an electron

donor and acceptor

Answer 24

Catalase

Question 25

Catalyze the removal of H ion from substrate using oxygen as hydrogen acceptor?

Answer 25

Oxidases

Question 26

Under most conditions in Vivo, | the activity seems to be favored?

Answer 26

Catalase

Question 27

Proteins that bind specific | glycosyl residues

Answer 27

Lectins

Question 28

Which is true about entropy?

Answer 28

Max as equilibrium is | approached

Question 29

``` Superoxidase dismutase removes/protects organisms against superoxide. T or F? ```

Answer 29

Throw

Question 30

First law of thermodynamics

Answer 30

Energy of a system can only be transferred/transformed

Question 31

Intermediate is acetyl coa

Answer 31

Leucine

Question 32

Ketogenic a.a

Answer 32

Leucine

Question 33

Driving force for proton

Answer 33

enters ATP synthase to | produce atp

Question 34

Fi has ___beta and ___ alpha

Answer 34

3 beta and 3 alpha

Question 35

Vit for succinate | dehydrogenase:

Answer 35

Niacin

Question 36

Non essential a.a produced by | body by

Answer 36

transamination

Question 37

Essential a.a can be acq thru

Answer 37

Diet

Question 38

If there is dec in insulin, lipgenesis and gluconeogenesis will inc

Answer 38

False

Question 39

Uncouplers are:

Answer 39

brown adipose tissue that functions to generate body heat

Question 40

Physical metabolic act increases | metaboloc rate by

Answer 40

40-50%

Question 41

Breakdown of tag to fatty acid

Answer 41

Lipoprotein lipase

Question 42

True of chylomicrons

Answer 42

cannot be taken up by liver

Question 43

When fatty acid is hydrolyzed it is directly taken up by the brain or erythrocytes

Answer 43

False

Question 44

What enzyme catalyzes anaplerotic reaction from pyruvate to oxaloacetate

Answer 44

Pyruvate carboxylase

Question 45

how many atps will be produced of the reducing eq in 1cycle of atp up to respiratory chain

Answer 45

9 ATP

Question 46

intermediates of Acetyl COA | and gluconeogenesis are the ff except:

Answer 46

Threonine

Question 47

Total number of atp produced | in the matrix

Answer 47

25 ATP

Question 48

inhibits oxidative phosphorylation by inhibiting thetransporter of ADP into and ATP out of the mitochondrion

Answer 48

Atractyloside

Question 49

Direct reduction of Ubiquinone(Q) by succinate dehydrogenase

Answer 49

complex 2

Question 50

Substrate that combines with Acetyl CoA for citric acid cycle to proceed

Answer 50

Oxaloacetate

Question 51

Co factors of alpha | ketoglutarate

Answer 51

aota (COA, NAD thiamine | diphosphate etc)

Question 52

Oxidation of one QH2

Answer 52

coupled to the reduction of two molecules of cytochrome c

Question 53

activates glycogen | phosphorylase

Answer 53

Glucagon

Question 54

Availability of ADP ONLY | State 4

Answer 54

Resting state

Question 55

Flavin nucleotides

Answer 55

Complex 1&2

Question 56

Malate dehydrogenase | requirement

Answer 56

Niacin

Question 57

What does not occur in | erythrocytes

Answer 57

B-oxidation of FA

Question 58

Creatine phosphate shuttle

Answer 58

transport of high energy | phosphate

Question 59

Inhibited by Malonate/Malonate will accumulate this enzyme

Answer 59

Succinate dehydrogenase

Question 60

cannot be synthesized by body thus must be supplied in the diet

Answer 60

Essential amino acids

Question 61

can be synthesized by the | body

Answer 61

Non-essential amino acids

Question 62

Total ATP in the mitochondrial | matrix

Answer 62

25

Question 63

Amino acid that will produce | acetyl CoA only/purely ketogenic

Answer 63

Lysine/Leucine

Question 64

Oxidation of reducing equivalents will give a total ATP in | citric acid cycle of

Answer 64

Resting state Availability of ADP only (State 4)

Question 65

Physical activity increases basal | metabolic rate by

Answer 65

40-50%

Question 66

Erythrocytes are purely | dependent on

Answer 66

PPP

Question 67

Uses Acetyl COA as substrate

Answer 67

Citrate synthase

Question 68

Protein metabolism in fasting | state

Answer 68

0.2/20%

Question 69

Vitamin needed for electron | acceptor of malate dehydrogenase

Answer 69

Niacin

Question 70

True of uncouplers

Answer 70

Found in brown adipose | tissue

Question 71

Which doesn’t occur in RBCs

Answer 71

betaoxidation

Question 72

True of glucagon

Answer 72

vactivates glycogen | phosphorylase in the liver

Question 73

True of succinate | dehydrogenase

Answer 73

contains FAD and Fe-S

Question 74

Lack of insulin leads to gluconeogenesis true or false

Answer 74

Throw

Question 75

True of creatinine phosphate | shuttle

Answer 75

transfer of high energy phosphate from mitochondria

Question 76

Proton motive force:

Answer 76

drives ATP synthesis

Question 77

True of Acetyl-Coa from betaoxidation

Answer 77

can be used to synthesize | acetone and acetoacetate

Question 78

True of chylomicrons

Answer 78

not directly taken up by the | liver

Question 79

Key enzyme that catalyzes net transfer out of TCA into gluconeogenesis

Answer 79

phosphoenolpyruvate | carboxykinase

Question 80

Enzyme that directly reduces | ubiquinone

Answer 80

succinate dehydrogenase

Question 81

True of Fe-S proteins

Answer 81

found in complexes I, II and | III

Question 82

NAD as electron acceptor

Answer 82

Malate dehydrogenase

Question 83

T or F: Fatty acids from lipolysis are directly taken up by the brain and rbc

Answer 83

falls

Question 84

Sites of regulation for TCA

Answer 84

citrate synthase and | pyruvate dehydrogenase

Question 85

Mechanism of ATP synthase

Answer 85

F1 has 3 alpha and 3 beta | subunits that do not rotate