PREFI - VITAMINS, LIPID TRANSPORT, RBC/WBC, CHOL METABOLISM (2022) Flashcards

(56 cards)

1
Q

Pruritis and Headache is a symptom of?

A

Hypervitaminosis

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2
Q

All of the ff are symptoms of Hypervitaminosis EXCEPT;

A

Splenomegaly

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3
Q

Riboflavin is used in these pathways EXCEPT

A

Glycolysis

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4
Q

Dihydrofolate reductase inhibitor

A

Trimethoprim

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5
Q

Dietary Folic acid requirement

A

0.4 mg

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6
Q

Deficiency of biotin

A

Ingestion of avidin

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7
Q

Plant source of vitamin D

A

Ergocalciferol

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8
Q

Night blindness

A

Destroyed visual

cells

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9
Q

Dry, keratinization and blindness of conjunctiva

A

Xeropthalmia

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10
Q

Dry skin and progressive paralysis

A

Vitamin B1

Thiamine

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11
Q

Vegetarian will become deficient of

A

Vitamin B12

Cobalamin

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12
Q

Site of synthesis of retinol

A

Retina

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13
Q

Coenzyme of Amino acid metabolism in transamination and

decarboxylation

A

Pyridoxal PO4

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14
Q

Which of the ff is not a characteristic of scurvy?

A

Demineralization

of bone

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15
Q

What causes Folate trap?

A

Vitamin B12

deficiency

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16
Q

What prevents oxidation of PUFA(PolyunsaturatedFattyacid)

A

Vitamin E

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17
Q

Lactic acidosis is seen in deficiency of?

A

Vitamin B1

thiamine

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18
Q

Carcinoid is associated with

A

Niacin

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19
Q

Activate glutamate residue to form carboxyglutamate

A

Vitamin K

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20
Q

Hemolytic Anemia in premature infants

A

Vitamin E

deficiency

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21
Q

Adult w/ Vitamin A deficiency, should take

A

More than 1000

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22
Q

Prolonged use of antibiotic will lead to

A

Vitamin K

deficiency

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23
Q

Antibiotic that causes Vitamin K deficiency

A

Cephalosporin

24
Q

Primary function, as antioxidant in prevention of non-enzymatic
oxidation of cell components and free radicals

25
Cofactor of A-ketoglutarate dehydrogenase
Thiamine | pyrophosphate
26
The 1st cell that responds on inflammation
Neutrophils
27
Which of the ff does not belong to the group?
Lymphocyte *PS Lymphocyte and Monocyte = AGRANULOCYTE
28
All cell lines comes from what cell line
Hemoblast
29
Vitamin K deficiency will lead to the decrease in production of what factor?
Prothrombin
30
Erythroblastosis fetalis in common in
``` Mother Rh (-) Baby Rh (+) ```
31
Type AB contains _____ antigen and ______ antibodies
AB and Neither | Anti-A and Anti-B
32
The conversion of Heme to biliverdin
Heme oxygenase
33
Which of the ff is NOT true?
Biliverdin is | reabsorb back toBM
34
``` ABO antibodies are produced even before antigen exposure (Natural occurring antibodies) TRUE OR FALSE ```
TRUE
35
Allergic and Parasitic Infection cell involve is?
Eosinophil
36
Most abundant lipid in plasma
Cholesteryl ester
37
Most active plasma lipid
Unesterified FA
38
Responsible for transport of all dietary lipids in circulation
Chylomicron
39
Predominant lipoporotein in LDL
Cholesterol
40
Final stage in the catabolism of VLDL
LDL (Low density | lipoprotein)
41
Predominant lipoprotein in Chylomicrons
TAG
42
Apolipoprotein found in HDL
Apo A
43
Inhibitor of Lipoprotein lipase
Apo C III
44
Cofactor for LCAT (Lecithin:Cholesterol acyltransferase)
Apo A1
45
LDL predominantly has Cholesterol / TRUE OR FALSE
TRUE
46
Reverse transport
HDL
47
HDL major component is bile acids. TRUE OR FALSE
FALLS
48
Increase triglyceride synthesis and VLDL secretion
Ethanol
49
Competes with reducing equivalent from other substrates for | respiratory chain
NADH
50
Parent steroid compound of cholesterol
Lanosterol
51
Cholesterol ester storage disease
Wolman’s disease
52
Source of carbons in cholesteroL
Acetyl CoA
53
First and principal regulatory step in biosynthesis of Bile
Production of 7ahydroxylation of cholesterol
54
Which of the ff. is not a product of Bile hydrolysis
Calcitriol
55
Most abundant bile acid
Cholic acid
56
Modification of bile making alkaline bile to produce bile salts
Conjugation with glycine and taurine residues